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NCT06268470 Clinical Trial

Antiplatelet Therapy in Chronic Urticaria

Chronic Urticaria Clinical Trial

Official title:
Efficacy of Antiplatelet Therapy for the Treatment of Chronic Recalcitrant Urticaria

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT06268470
Other study ID # Chula-ARC 001/18
Secondary ID
Status Active, not recruiting
Phase Phase 2
First received
Last updated
Start date June 1, 2018
Est. completion date May 1, 2024

Study information
Verified date February 2024
Source Chulalongkorn University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study compares the combination of antiplatelets and antihistamine versus antihistamine alone for the treatment of chronic spontaneous urticaria

Description:

This study is a randomized control trial comparing the effectiveness of the combination of antiplatelets and antihistamine and antihistamine alone for the treatment of chronic spontaneous urticaria

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 12
Est. completion date May 1, 2024
Est. primary completion date March 1, 2024
Accepts healthy volunteers No
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: Chronic spontaneous urticaria D-dimer levels over 500 ng/ml Not respond to a conventional dose of antihistamine Exclusion Criteria: Are taking aspirin Have bleeding tendency Have concurrent severe medical illnesses -

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Desloratadine plus cilostazol and dipyridamole
Desloratadine 20 mg/day plus cilostazol 150 mg/day and dipyridamole 50 mg/day
• Desloratadine
Desloratadine 20 mg/day

Locations
Country Name City State
Thailand Faculty of Medicine, Chulalongkorn University Bangkok

Sponsors (1)
Lead Sponsor Collaborator
Chulalongkorn University

Country where clinical trial is conducted

Thailand, 

Outcome
Type Measure Description Time frame Safety issue
Primary Weekly urticaria activity score Urticaria activity score over 7 days (UAS7): scores 0-42 from mild to severe 4 weeks
Secondary D-dimer levels D-dimer levels 4 weeks
See also
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