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A Study to Assess the Efficacy and Safety of AK002 in Subjects With Antihistamine-Resistant Chronic Urticaria — CURSIG  

Chronic Urticaria Clinical Trial

Official title:
An Open-Label, Pilot Study to Assess the Efficacy and Safety of AK002 (Siglec-8) in Subjects With Antihistamine-Resistant Chronic Urticaria

Clinical Trial Summary

This is a Phase 2a, open-label study to assess the effects of AK002

Clinical Trial Description

This open-label study is to assess the effects of AK002, given as monthly intravenous infusions at up to 3 mg/kg. A total of 47 patients will be enrolled across 2-4 sites. All patients enrolled in the study will receive 6 monthly infusions of AK002 and will then be followed for another 8 weeks. Some patients will have the option to receive an additional 12 months of extended dosing. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03436797
Study type Interventional
Source Allakos Inc.
Contact
Status Completed
Phase Phase 2
Start date January 23, 2018
Completion date April 6, 2020
View Details
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