Chronic Total Occlusion Clinical Trial
Official title:
Investigating the Utility of Remote Index of Microvascular Resistance in Patients With Chronic Total Occlusion
This is prospective cohort study in subjects with a planned percutaneous coronary intervention (PCI) of their chronic total occlusion (CTO). The study will enroll subjects who have been scheduled for a clinically-indicated cardiac catheterization, and will evaluate coronary microvascular function in all subjects meeting inclusion criteria with a coronary flow wire. Evaluation of coronary microvascular function may be performed using indirect methods, however the rationale behind the present study is to directly measure microvascular function using direct coronary flow measurements, since the subjects in the study are to undergo a clinically-indicated cardiac catheterization. The overall purpose of the study is to define the presence and severity of coronary microvascular dysfunction subjects with CTO. The study is designed to enroll 50 subjects with CTO in the span of 3 years. There will be a 6-month assessment of the outcomes of death and cardiovascular death. As the study includes FDA approved tests, there will be no safety endpoint per se, however there will be a mechanism for monitoring adverse events as will be described in detail.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05111496 -
Evaluation of the Radiological Dose Delivered to Risky Interventional Cardiology Patients (Optidose)
|
||
Not yet recruiting |
NCT05440084 -
Impact of CTO PCI (Chronic Total Occlusion Percutaneous Intervention) on Regular Physical Activity
|
||
Withdrawn |
NCT04059536 -
Registry Study to Evaluate the Performance and Safety of Roxwood Medical Catheters in Arteries of Participants With a Stenotic Lesion or Chronic Total Occlusion (CTO)
|
||
Completed |
NCT05158686 -
Use of Drug-Coated Balloon to Improve Recanalization of a Coronary Chronic Total Occlusion After Failed Angioplasty
|
||
Completed |
NCT03988166 -
Chronic Total Occlusion Percutaneous Coronary Intervention Study
|
N/A | |
Not yet recruiting |
NCT06175377 -
Antiplatelet Therapy After Successful Percutaneous Coronary Intervention for Chronically Occluded Coronary Artery
|
N/A | |
Not yet recruiting |
NCT05632653 -
CTO-PCI in Heart Failure Patients
|
N/A | |
Recruiting |
NCT03563989 -
STENTYS Xposition S in the Treatment of Chronic Total Artery Occlusion
|
N/A | |
Recruiting |
NCT04710342 -
Clinical Study Evaluating Use of the CapBuster Medical Device System for the Crossing of Chronic Total Occlusions
|
N/A | |
Not yet recruiting |
NCT06358508 -
Sapphire 3 CTO Study
|
N/A | |
Completed |
NCT01246505 -
Peripheral Facilitated Antegrade Steering Technique in Chronic Total Occlusions
|
Phase 3 | |
Recruiting |
NCT05614180 -
Chronic Total Occlusive Lesions CMR Study
|
||
Recruiting |
NCT04533633 -
German Epicardial Collateral CTO Registry
|
||
Recruiting |
NCT04650139 -
Coronary Interventions Ulm - Coronary Chronic Total Occlusions
|
||
Recruiting |
NCT06137521 -
Risk Factors and Outcomes in Coronary Chronic Total Occlusion
|
||
Completed |
NCT02358629 -
A Prospective, Non-randomized Study to Evaluate the Safety and Performance of the NovaCross™ Microcatheter in Femoropopliteal Chronic Total Occlusion (CTO).
|
N/A | |
Completed |
NCT00670436 -
The Paclitaxel-Eluting Percutaneous Transluminal Coronary Angioplasty (PTCA) - Balloon Catheter in Coronary Artery Disease to Treat Chronic Total Occlusions
|
Phase 2 | |
Completed |
NCT04862559 -
A Single Center Study to Evaluate the Safety of the NovaCross Microcatheter in Crossing Chronic Total Occlusions
|
N/A | |
Active, not recruiting |
NCT02227771 -
Consistent CTO Trial
|
N/A | |
Recruiting |
NCT05458999 -
Decreasing Patient Anxiety During Revascularization of Chronic Total Coronary Occlusions Using Virtual Reality Glasses.
|
N/A |