Vitamin D Supplementation in Episodic and Chronic Tension-type Headache

Chronic Tension-Type Headache Clinical Trial

Official title: Evaluation of Vitamin D Supplementation in Patients With Episodic and Chronic Tension-type Headache.

Status Recruiting

Clinical Trial Summary

The goal of this clinical trial is to learn about the effect of vitamin D in patients with prophylactic therapy for episodic and chronic tension-type headache in amitriptyline or topiramate treatment. The main question it aims to answer are:

• What is the effect of vitamin D in patients with prophylactic therapy for episodic and chronic tension-type headache?

Patients will have the next selection criteria:

• Patients diagnosed by a neurologist in the headache clinic

• Criteria for episodic and chronic tension-type headache

• Poor clinical response to prophylactic treatment (amitriptyline, topiramate)

• Use of at least 1 prophylactic medication or a history of having used them.

• Onset of disease between the ages of 18 and 60

• Signature of informed consent

The population will be randomly divided into the following 3 treatment groups:

• Participants amitriptyline or topiramate treatment.

• Patients with placebo (Calcium) + topiramate/amitriptyline,

• Participants with vitamin D3/calcium+topiramate/amitriptyline. Researchers will compare the groups to see if vitamin D can decrease the intensity of your headache and therefore have a new therapeutic option.

Clinical Trial Description

It will be a 4 month study. Each month a package containing treatment will be delivered, which may be conventional medication or tablets with conventional medication added with vitamins. ;

Related Conditions & MeSH terms

• Chronic Tension-Type Headache
• Headache
• Tension-Type Headache

• NCT number: NCT05860062
• Study type: Interventional
• Source: Hospital de Especialidades, Centro Medico Nacional "La Raza", Instituto Mexicano del Seguro Social
• Contact: Mario A. Mireles Ramírez, Dr.
• Phone: 3336170060
• Email: especialidad.cmno@gmail.com
• Status: Recruiting
• Phase: N/A
• Start date: April 18, 2023
• Completion date: December 20, 2023