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Chronic Stable Heart Failure clinical trials

View clinical trials related to Chronic Stable Heart Failure.

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NCT ID: NCT05034549 Recruiting - Clinical trials for Chronic Stable Heart Failure

Noninvasive Ventilation for Chronic Heart Failure

Start date: August 5, 2019
Phase: N/A
Study type: Interventional

The effects of home noninvasive ventilation on renin-angiotensin system (RAS), kallikrein-kinin system (KKS) and cardiac remodeling in patients with chronic stable heart failure have not been reported. This project aims to clarify the efficacy and safety of home non-invasive ventilation in patients with chronic heart failure complicated with sleep-disordered breathing. First, patients with chronic stable heart failure were selected and monitored by polysomnography. Patients with sleep apnea hypopnea syndrome (SAHS, AHI≥15) were randomly divided into two groups: the treatment group was treated with non-invasive ventilator at home (≥5h/ night); The control group was only given routine treatment. After 6 months of follow-up, the effects of sleep disordered breathing and noninvasive ventilation on RAS, KKS, cardiac remodeling and function and cardiovascular adverse events in patients with chronic heart failure were evaluated. The results are helpful to further reveal the role of sleep disordered breathing in the occurrence and development of chronic heart failure, and provide a new diagnosis and treatment strategy for chronic heart failure.

NCT ID: NCT03834155 Recruiting - Clinical trials for Coronary Artery Disease

Enhancing Cardiac Rehabilitation Through Behavioral Nudges

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Adherence to cardiac rehabilitation is poor, and worse for minorities, women, and those with lower levels of education. Patients less likely to be referred to and complete cardiac rehab are at highest risk of adverse outcomes and thus have the most to gain from participation in cardiac rehab. To improve participation, healthcare systems need to limit barriers to enrollment and promote adherence to rehabilitation.

NCT ID: NCT01065194 Recruiting - Clinical trials for Chronic Stable Heart Failure

Efficacy and Safety of Pulsed Infusions of Levosimendan in Outpatients With Advanced Heart Failure

LevoRep
Start date: August 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to compare the effects of a pulsed application of Levosimendan versus placebo on the composite end-point functional capacity and quality of life.