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Extending Omalizumab Treatment Intervals in Patients With Chronic Spontaneous Urticaria — EXOTIC  

Chronic Spontaneous Urticaria Clinical Trial

Official title:
Extending Omalizumab Treatment Intervals in Patients With Chronic Spontaneous Urticaria (EXOTIC Trial): a Multicentre, Randomized, Open-label, Non-inferiority Trial

Clinical Trial Summary

This study is a multicentre, randomized, open-label, non-inferiority clinical trial. The purpose and aim of this study is to investigate if patients with well controlled (UCT score score ≥ 12) chronic spontaneous urticaria (CSU) on omalizumab 300 mg every four weeks can extend treatment intervals and maintain disease control.

Clinical Trial Description

Newly referred patients with CSU who are well-treated (UCT score ≥ 12) 12 weeks after initiating standard treatment with omalizumab 300 mg every four weeks, are randomized into two treatment arms.The first arm will continue standard treatment with omalizumab 300 mg every four weeks for 24 weeks. The second arm will receive treatment in an extended interval of omalizumab 300 mg every six weeks for 24 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05916937
Study type Interventional
Source Bispebjerg Hospital
Contact Simon F Thomsen, MD, DMSc
Phone +4526139838
Email simon.francis.thomsen.02@regionh.dk
Status Recruiting
Phase Phase 4
Start date January 12, 2024
Completion date June 1, 2025
View Details
See also
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