Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbations

Status Completed

Clinical Trial Summary

The purpose of this study is to treat patients with a diagnosis of chronic rhinosinusitis (CRS) and a history of bilateral endoscopic sinus surgery during times of worsening symptoms and signs of acute infection on nasal endoscopy with one of two treatments: (1) oral antibiotics and twice daily intranasal saline irrigations or (2) oral placebo and twice daily intranasal antibiotic irrigations. The two treatments will be compared to see if there is any difference in patient outcomes. This will help guide treatment strategies for patients with CRS in the future.

Clinical Trial Description

See brief summary. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01988779
Study type	Interventional
Source	University of Rochester
Contact
Status	Completed
Phase	Phase 3
Start date	October 2013
Completion date	December 31, 2020

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