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Breath Analysis and Arterial Stiffness in Patients With Respiratory Diseases

Cystic Fibrosis Clinical Trial

Official title:
Exhaled Breath Proton Mass Spectrometry and Assessment of Endothelial Dysfunction in Patients With Respiratory Diseases

Clinical Trial Summary

Assessment of cardiovascular disorders using echocardiography and arterial stiffness; comparative noninvasive assessment of volatile organic compound (eVOC) exhale breath patterns in patients with different chronic respiratory diseases with age and gender-matched healthy adults in order to identify a disease-specific exhaled eVOCs profiles and markers of respiratory and cardiovascular disorders.

Clinical Trial Description

Evaluating of eVOCs profiles by proton mass spectrometry with a time-of-flight (PTR-TOF) in patients with different chronic respiratory diseases is of great interest for assessing the prognosis and development of severe ventilation and cardiovascular disorders. The aim of our study is to determine the diagnostic significance of PTR-TOF analysis in patients with chronic respiratory diseases and to identify specific eVOC markers of a severe ventilation and cardiovascular disorders in patients with different chronic respiratory diseases. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05727852
Study type Observational
Source I.M. Sechenov First Moscow State Medical University
Contact
Status Enrolling by invitation
Phase
Start date January 30, 2023
Completion date December 2026
View Details
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