Pelvic Pain Clinical Trial
Official title:
Open-Label Study of Thalidomide for Chronic Prostatitis/Chronic Pelvic Pain
To determine the efficacy of thalidomide for treatment of the Chronic Pelvic Pain Syndrome (CPPS).
Prostatitis is the most common urologic diagnosis in men under the age of 50 and the third
most common diagnosis in older men. In Chronic Prostatitis (CP) or Chronic Pelvic Pain
Syndrome (CPPS), men have lower urinary tract symptoms, pelvic pain, sexual dysfunction and
decreased quality of life. Little is known about the cause of CP/CPPS and no definitive
therapy exists.
Thalidomide is an immunomodulator (a drug that alters the immune system) and it may also
interfere with the development of tiny blood vessels that help support tumor growth.
Therefore, in theory, it may reduce or prevent the growth of cancer cells. Thalidomide is
approved by the Food and Drug Administration (FDA) for a leprosy skin condition, but not for
the treatment of CP or CPPS.
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Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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