Chronic Plaque Psoriasis Clinical Trial
Official title:
Topical Vitamin B12 in Chronic Plaque Psoriasis
Objective: To test the efficacy and tolerability of a vitamin B12 cream for the treatment of
chronic plaque psoriasis.
Design: Multicenter, double-blind, randomized, placebo-controlled trial.
Objective: To test the efficacy and tolerability of a vitamin B12 cream for the treatment of
chronic plaque psoriasis.
Design: Multicenter, double-blind, randomized, placebo-controlled trial. Setting: ambulatory
patients in research or referral centers. Patients: Volunteer sample of 51 patients with
chronic plaque psoriasis. Interventions: All Patients applied vitamin B12 cream twice daily
for 8 weeks to one side of the body and placebo to the other.
Main outcome measures: Modified Psoriasis Area and Severity Index (PASI) at weeks 0, 2, 4, 6
and 8. Thickness and density of 3 references plaques determined by 20 MHz sonography.
Assessment of efficiency and tolerability by patients and investigators.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT03598790 -
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
|
Phase 3 | |
| Completed |
NCT00799877 -
Chronic Plaque Psoriasis (Ps) Registry
|
||
| Completed |
NCT02581345 -
Phase 3 Study of M923 and Humira® in Subjects With Chronic Plaque-type Psoriasis
|
Phase 3 | |
| Withdrawn |
NCT01200264 -
Apremilast for Chronic Plaque Psoriasis (CPP) Patients Who Have Failed One Course of Biologic Therapy
|
Phase 2 | |
| Not yet recruiting |
NCT00707070 -
Combining Acitretin and Efalizumab in the Therapy of Chronic Plaque Psoriasis
|
Phase 4 | |
| Terminated |
NCT00972543 -
Raptiva in Palm and Sole Psoriasis
|
Phase 4 | |
| Completed |
NCT00539929 -
Paired-Comparison Study Evaluating the Efficacy and Safety of E6201 Versus Vehicle for the Treatment of Plaque-Type Psoriasis
|
Phase 2 | |
| Completed |
NCT02852967 -
A Phase 2, Double-blind, Placebo-controlled Study of the Efficacy and Safety of Belumosudil in Subjects With Moderate/Severe Chronic Plaque Psoriasis
|
Phase 2 | |
| Completed |
NCT00770965 -
Phase II Efficacy Study Looking at a Single-dose of One of Three Dose Levels of AIN457 in Patients With Chronic Plaque-type Psoriasis
|
Phase 2 | |
| Active, not recruiting |
NCT06011733 -
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Chinese Adult Study Participants With Moderate to Severe Plaque Psoriasis
|
Phase 3 | |
| Completed |
NCT00245765 -
Efficacy Study of CDP870 in Subjects With Chronic Plaque Psoriasis Who Are Candidate for Systemic Therapy and/or Phototherapy/Photochemotherapy
|
Phase 2 | |
| Completed |
NCT00673556 -
A Study to Assess the Efficacy and Safety of Alefacept in Psoriasis Patients for Whom Conventional Treatment is Ineffective or Inappropriate
|
Phase 3 | |
| Terminated |
NCT00844363 -
Narrowband UVB Phototherapy in the Treatment of Psoriasis Vulgaris
|
N/A | |
| Completed |
NCT00574249 -
Adalimumab in Combination With Topical Treatment (Calcipotriol/Betamethasone) in Subjects With Moderate to Severe Psoriasis and Insufficient Response to Classic Systemic Treatment
|
Phase 3 | |
| Completed |
NCT00512187 -
Moderate Weight Loss Makes Obese Patients With Severe Chronic Plaque Psoriasis Responsive to Sub-Optimal Dose of Cyclosporine: an Investigator Blinded, Controlled, Randomized Clinical Trial
|
Phase 4 | |
| Completed |
NCT02570750 -
The Effect Of Smoking Status Of The Patient On The Success Of Etanercept Therapy In Psoriasis
|
||
| Completed |
NCT00438360 -
Efficacy and Safety of Cyclosporine A Microemulsion in Maintenance Patients With Chronic Plaque Psoriasis
|
Phase 3 | |
| Active, not recruiting |
NCT03897075 -
Efficacy and Safety Study of Tildrakizumab in the Treatment of Nail Psoriasis
|
Phase 3 | |
| Completed |
NCT01358578 -
Safety and Efficacy of Secukinumab Compared to Etanercept in Subjects With Moderate to Severe, Chronic Plaque-Type Psoriasis
|
Phase 3 | |
| Completed |
NCT03536884 -
A Study to Evaluate the Efficacy and Safety of Bimekizumab Compared to an Active Comparator in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis
|
Phase 3 |