Laser Assisted Nonsurgical Periodontal Treatment

Chronic Periodontitis Clinical Trial

Official title:

Clinical and Microbiologic Effects of Nonsurgical Periodontal Treatment Combined With an Erbium: Yttrium Aluminium Garnet Laser

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03387371
• Other study ID #: LaserPerio001
• Status: Active, not recruiting
• Phase: N/A
• First received: November 7, 2017
• Last updated: December 29, 2017
• Start date: July 18, 2016
• Est. completion date: January 20, 2018

Study information

• Verified date: November 2017
• Source: Bezmialem Vakif University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Periodontitis is a chronic inflammatory disease caused by mixed infections with the subgingival microbiota being organized as a biofilm that, if untreated, may result in breakdown of the periodontal tissues in susceptible individuals. Evidence from intervention studies shows that mechanical root debridement significantly improves periodontal health by halting the progression of periodontal tissue breakdown. In order to improve effectiveness and efficacy of the removal of the subgingival biofilm, Er:YAG laser therapy has recently been recommended as an alternative to conventional scaling procedures.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 38
• Est. completion date: January 20, 2018
• Est. primary completion date: January 20, 2018
• Accepts healthy volunteers: No
• Gender: All
• Age group: 28 Years to 58 Years

Eligibility

Inclusion Criteria:

Greater than 25 years, Clinical diagnosis of moderate to advanced chronic periodontitis, Pocket depth = 5 mm or clinic attachment level = 4 mm at least in two interproximal areas (not on the same tooth), Along with very good oral hygiene scores (GI=1and PI=1), At least 4 teeth in each quadrant, Teeth with subgingival plaque sample is collected has no restoration or prothesis

Exclusion Criteria:

Periodontal treatment ( root planning or surgical periodontal treatment) had done before, Systemic disease that could influence the outcome of periodontal therapy, Prophylaxis regime mandatory during periodontal treatment, Use of any drug that could influence the outcome of periodontal therapy, Use of antibiotics within the last 3 months, Use of anti-inflammatory drugs within the last 3 months, Use of removable prothesis Pregnancy, lactation or use of hormone contraceptives, Smoking

Related Conditions & MeSH terms

• Chronic Periodontitis
• Periodontitis

Intervention

Device:
• Ultrasonics
ultrasonic scalers
• Gracey Curettes
Spesific gracey curettes
• Er:YAG Laser
2940 nm wavelenght Er:YAG laser

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Bezmialem Vakif University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Probing Pocket Depth 3	to measure the probing pocket depth of all teeth	3. month
Primary	Clinic Attachment Level 3	to measure the Clinic Attachment Level of all teeth	3. month
Primary	Subgingival Plak Sample 1	quantitative changes on red complex bacterias	1. month
Primary	Probing Pocket Depth 6	to measure theProbing Pocket Depth of all teeth	6. month
Primary	Clinic Attachment Level 6	to measure the Clinic Attachment Level of all teeth	6. month
Primary	Subgingival Plak Sample 3	quantitative changes on red complex bacterias	3. month
Primary	Subgingival Plak Sample 6	quantitative changes on red complex bacterias	6. month
Secondary	Bleeding On Probing 3	to record the Bleeding On Probing of all teeth	3. month
Secondary	Bleeding On Probing 6	to record the Bleeding On Probing of all teeth	6. month
Secondary	Plak Index 3	to record the plak index of all teeth	3. month
Secondary	Plak Index 6	to record the plak index of all teeth	6. month