Chronic Periodontitis Clinical Trial
Official title:
Diode Laser Therapy As An Adjunct To Non-Surgical Management Of Chronic Periodontitis - A Pilot Study
Laser therapy has been proposed as a novel treatment option in controlling subgingival microorganisms. This randomized controlled clinical trial evaluates the effect of 980nm diode laser as an adjunct to scaling and root planing (SRP) in the management of chronic periodontitis (CP).
Conventional mechanical debridement can achieve a temporary decrease in the subgingival
levels of Pg along with other pathogens. However, mechanical therapy alone may fail to
eliminate pathogenic bacterial niches in inaccessible areas like deep pockets, root
concavities, furcation areas etc. In search of more efficient and less traumatic techniques
to improve periodontal healing, researchers proposed the use of lasers in periodontal
therapy.
The adjunctive use of lasers with conventional tools may facilitate treatment and have the
potential to improve healing. The diode laser is highly absorbed in hemoglobin and other
pigments and is excellent for use in soft tissue surgical procedures.Laser application in
improving clinical outcome in periodontal therapy, needs to be further investigated with
well designed clinical trials. The investigators attempted to evaluate the efficacy of diode
laser as an adjunct to SRP in the management of CP by evaluating clinical parameters coupled
with quantitative estimation of P.gingivalis using Real-time Polymerase chain reaction
(RT-PCR) assay.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Not yet recruiting |
NCT06400069 -
Role of NLRP6 in Chronic Periodontitis
|
||
Completed |
NCT05231096 -
Comparison of the Effect of Gingival Massage of Aloe-vera Gel and Sidr Honey on Chronic Periodontitis
|
N/A | |
Completed |
NCT03203746 -
Gingival Crevicular Fluid Levels of Protein Carbonyl Following the Use of Lycopene in Chronic Periodontitis
|
Phase 1/Phase 2 | |
Active, not recruiting |
NCT03354338 -
Amoxicillin to Prevent Bacteria and Inflammatory Biomarkers After Intensive Periodontal Therapy
|
Phase 2 | |
Completed |
NCT02516111 -
Comparison of Autologous PRF, 1% Alendronate and 1.2% Atorvastatin Gel in Chronic Periodontitis Treatment
|
Phase 2/Phase 3 | |
Terminated |
NCT02568163 -
Influence of Stress on Non Surgical Periodontal Treatment
|
N/A | |
Completed |
NCT02174146 -
Leptin and Visfatin in Diabetic Patients With Periodontitis Before and After Periodontal Therapy
|
N/A | |
Completed |
NCT02430519 -
Benefits of Platelet Rich Fibrin In Mandibular Molar Furcation Defects
|
N/A | |
Completed |
NCT01438333 -
Efficacy of INERSAN in Patients With Chronic Periodontitis as Adjunctive to Full Mouth Disinfection
|
N/A | |
Completed |
NCT01233765 -
Analysis of Neutrophil Response in Chronic Periodontitis
|
N/A | |
Completed |
NCT02218515 -
Treatment of Intrabony Periodontal Defects With Enamel Matrix Derivatives and Autogenous Bone Graft
|
Phase 4 | |
Completed |
NCT02197260 -
Antimicrobial Therapy as Adjunct to Periodontal Treatment: Effect of Timing
|
Phase 4 | |
Not yet recruiting |
NCT03270280 -
Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis
|
Phase 2 | |
Not yet recruiting |
NCT04026828 -
Evaluation of Possible Genes in Periodontal Diseases by Genetic Methods
|
||
Completed |
NCT04697199 -
The Adjunctive Effect of Probiotics to Non Surgical Treatment of Chronic Periodontitis
|
Phase 1 | |
Completed |
NCT04643288 -
Nanocrystalline Hydroxyapatite Bone Substitute for Treating Periodontal Intrabony Defects
|
N/A | |
Completed |
NCT03039244 -
Evaluation of Antimicrobial Photodynamic Therapy as an Adjunct to Periodontal Treatment in Smokers
|
N/A | |
Completed |
NCT02851823 -
Combined Use of Er:YAG and Nd:YAG Laser
|
N/A | |
Completed |
NCT02898675 -
Advantages of Autologous Platelet-Rich Fibrin Membrane on Growth Factor Levels and Periodontal Healing
|
N/A | |
Completed |
NCT02518152 -
Platelet Rich Fibrin+1% Alendronate in Treatment of Chronic Periodontitis
|
Phase 2/Phase 3 |