Chronic Periodontitis Clinical Trial
Official title:
Effects of Nonsurgical Periodontal Therapy on Plasma Hepatocyte Growth Factor Levels in Smokers and Non Smokers With Chronic Periodontitis
This study is intended to measure hepatocyte growth factor levels in smokers and non smokers with periodontitis before and after non surgical periodontal therapy.
The study was randomised prospective,interventional clinical trial. The sample size for the
study was 40 individuals aged between 20 to 60 years,equally divided into two groups.
Group l - smokers with chronic periodontitis (test) group. Group ll - non smokers with
chronic periodontitis (controls)
At baseline both the groups were analysed for clinical and biochemical parameters and
underwent non surgical periodontal therapy( scaling and root planning). All parameters were
reassesed after 3 months.
A total of 40 patients( 20 somkers and 20 non smokers) from the outpatient wing of
department of periodontics, Panineeya mahavidyalaya institute of dental sciences and
research centre diagnosed with chronic periodontitis and willing to participate in the
study.
Clicical parameters included gingival index and periodontal index. Biochmeical parameters
included plasma hepatocyte growth factor.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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