Chronic Pancreatitis Clinical Trial
Official title:
Predictors of Pain Relief and Stone Fragmentation in Patients Undergoing Extra Corporeal Shock Wave Lithotripsy for Chronic Pancreatitis
Extra corporeal shock wave therapy (ESWL) is recommended for pain management in patients with
stone formation in pancreatic duct. ESWL can cause complete stone fragmentation and removal
in 70% patients, associated with 85 to 90% pain relief.
Investigators aim to study, predictors pain relief in patients who undergo ESWL, to find out
which patients will improve and which patients won't improve in terms of pain.
The study will be a single center observational study.
General information of the patient in form of duration of symptoms and duration of
diagnosis,exocrine and endocrine insufficiency. Imaging findings such as main pancreatic duct
stone,size,parenchymal calcification , ductal stricture and its location, using any
medications such as antioxidants and pain killers .
The pain score will be estimated by Izbicki's pain score in last 6 months. Patients will
receive standard of care during study period, and they won't receive any experimental
therapy.
After 6months of ESWL further general information of the patient any addictions, a formal
imaging and determining main pancreatic duct stone ,size ,calcifications and strictures and
also usage of any medications for decreasing pain.
Pain will be calculated by Izbick's pain score in last 6 months . Comparing pain score and
information investigators will evaluate predictive factors of pain relief after ESWL by
logistic regression.
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