Study of rTMS Analgesic Effect in Chronic Neuropathic Pain, — NEUROSTIM  

Chronic Neuropathic Pain Clinical Trial

Official title: Randomized Double-blind Study of rTMS Analgesic Effect in Chronic Neuropathic Pain. Comparison Between Three Groups: Motor Cortex Stimulation by the Classic Coil B65, Deeper Stimulation by the Coil B70 and Placebo Stimulation. Analysis of Long-term rTMS-induced Brain Changes Using fMRI.

Status Recruiting

Clinical Trial Summary

The purpose of this study is to compare the analgesic effectiveness of three modes of repetitive Transcranial Magnetic Stimulation (rTMS) in chronic neuropathic pain:

• Classical rTMS stimulation

• Deeper rTMS stimulation

• Sham rTMS stimulation

Clinical Trial Description

Conduct of study:

• Entry into the study: After informed consent, patients will be randomised. The physician responsible for conducting neurostimulation sessions will make the randomization via an interactive web response system (IWRS). Only this physician will have the knowledge of the group allocated to the patient.

• Baseline : Patients, will record on a diary form, a daily Visual Numeric Scale(VNS) of Pain Intensity for 1 week.

• Treatment sessions: after the baseline, sessions of neurostimulation will begin for seven weeks.

• After the end of neurostimulation sessions, patients will be followed for 2 weeks.

• Throughout their participation in the study, patients will plot on a diary form their daily VNS. ;

Related Conditions & MeSH terms

• Chronic Neuropathic Pain
• Neuralgia

• NCT number: NCT04936646
• Study type: Interventional
• Source: University Hospital, Grenoble
• Contact: Hasan HODAJ, MD
• Phone: 04-76-76-52-13
• Email: HHodaj@chu-grenoble.fr
• Status: Recruiting
• Phase: N/A
• Start date: July 16, 2021
• Completion date: December 1, 2024