The Efficacy Of Lidocaine Infusion IN Chronic Unilateral Migraine Headache

Status Active, not recruiting

Clinical Trial Summary

STUDY THE EFFICACY OF INTRAVENOUS LIDOCAINE INFUSION ON PATIENTS WITH CHRONICUNILATERAL MIGRAINE HEADACHE ..NO OF PATIENTS 80..WILLBE DIVIDED INTO 2 GROUPS..FIRST WILL RECEIVE MEDICAL TREATMENT PLUS LIDOCAINE INFUSION ONCE WEEKLY FOR 4 SUCCESIVE WEEKS ,OTHER WILL RECEIVE MEDICAL TREATMENT PLUS SALINE INFUSION SAME REGIMNE,FOLLOW UP USING MONTHLY MIGRAINE DAYS,VAS SCORE,MIDAS SCORE,QUALITY OF LIFE QUESTIONAIRE,PRE AND POST MEASUREMENT OF CALCITONIN GENE RELATED PEPTIDE

Clinical Trial Description

Group A will receive medical treatment for migraine plus normal saline infusion,Group B will receive medical treatment plus lidocaine infusion at dose from 3 to 4 mg per kg,computer generated random number will be used to identify the selected blocks and give the sequence of patients allocation,guarantee equal random in each group a set of permuted blocks will be generated. Each block has 4 differently ordered treatment assignments.Block 1 (AABB),Block2(ABAB),Block3(BABA),Block 4(ABBA),Block5(BAAB),Block 6(BBAA). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06109389
Study type	Interventional
Source	Alexandria University
Contact
Status	Active, not recruiting
Phase	Phase 2
Start date	October 1, 2023
Completion date	June 1, 2024

View Details

See also
Status	Clinical Trial	Phase
Terminated	`NCT04520425` - Osteopathic Manipulative Techniques for the Treatment of Chronic Migraine Headaches	N/A
Recruiting	`NCT06247592` - Pulse Radiofrequency and Occipital Nerve Block for Chronic Migraine Patients	N/A
Recruiting	`NCT06133491` - Open Label, 6-month Study for High Frequency and Chronic Migraine,
Recruiting	`NCT04989413` - Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg vs Placebo as Adjuvant Treatment in Chronic Migraine -	Phase 4
Recruiting	`NCT06138171` - Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia
Completed	`NCT04871581` - Adjunctive Treatment of Chronic Migraine Using an Oral Dental Device	N/A
Withdrawn	`NCT01749423` - A Retrospective Study to Evaluate the Effectiveness of onabotulinumtoxinA in Preventing Headaches in Patients With Chronic Migraines	N/A
Terminated	`NCT04349176` - Onabotulinum Dose Comparison in Chronic Migraine Superior to 100 Units?	Phase 3
Completed	`NCT05381129` - The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine	N/A
Completed	`NCT05381012` - Fibromyalgia Syndrome on Patients With Chronic Migraine	N/A
Withdrawn	`NCT03465826` - Developing a Mobile Health Pain-Coping Skills Training Program for the Treatment of Chronic Migraine: AIM 4	N/A
Completed	`NCT03767062` - Peripheral Nerve Block and Topiramate in the Treatment of Medication Overuse Headaches	N/A
Completed	`NCT05748535` - Effect of Auricular Vagus Nerve Stimulation in Women With Migraine Disease	N/A
Recruiting	`NCT05724771` - COACT Study: CGRPmAbs + OnabotulinumtoxinA Assessment of Chronic Migraine Treatments Study	Phase 4
Recruiting	`NCT05313503` - KETOMIGRAINE: Ketogenic Diet in Drug-resistant Chronic Migraineurs	N/A
Recruiting	`NCT05079659` - Rate , Predictors and Outcome of Chronic Migraine
Completed	`NCT06118190` - Mesotherapy in the Treatment of Chronic Migraine	N/A
Completed	`NCT03698409` - Onabotulinumtoxin Type A Reconstitution With Preserved Versus Preservative-free Saline in Chronic Migraine.	Phase 4
Completed	`NCT04017741` - A Study Investigating the Efficacy of GON Blocks.	Phase 4
Completed	`NCT05679908` - A Study to Evaluate the Efficacy and Safety of TNX-1900 in Patients With Chronic Migraine	Phase 2