Chronic Migraine, Headache Clinical Trial
Official title:
Comparison of Effects of Peripheral Nerve Block and Topiramate in the Treatment of Medication Overuse Headaches: A Randomised Parallel Group Study
Purpose: In this study, the investigators compared the effectiveness of peripheral nerve
block (greater occipital nerve block with supratrochlear nerve block) versus topiramate as
detoxification therapies in chronic migraine patients with medication overuse headache.
Methods: At least ninety chronic migraine patients with medication overuse headache are aimed
to include in this study. Patients will be divided into the two groups. The first group will
receive topiramate (n=45, estimated) and the second group will receive nerve block (n=45,
estimated) as detoxification therapy. Patients' records regarding the visual analog scale
(VAS) scores and headache frequencies are aimed to be collected before and after the therapy.
Comparisons regarding VAS scores, headache frequencies, 50% responder rates and 75% responder
rates will be performed in between topiramate and nerve block groups.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Terminated |
NCT04520425 -
Osteopathic Manipulative Techniques for the Treatment of Chronic Migraine Headaches
|
N/A | |
| Recruiting |
NCT06247592 -
Pulse Radiofrequency and Occipital Nerve Block for Chronic Migraine Patients
|
N/A | |
| Recruiting |
NCT06133491 -
Open Label, 6-month Study for High Frequency and Chronic Migraine,
|
||
| Recruiting |
NCT04989413 -
Cannabidiol 133mg + Cannabigerol 66mg + Tetrahydrocannabinol 4mg vs Placebo as Adjuvant Treatment in Chronic Migraine -
|
Phase 4 | |
| Recruiting |
NCT06138171 -
Personality, Defences, Central Sensitization, and Trauma in Women With Chronic Migraine, Fibromyalgia, and Vulvodynia
|
||
| Active, not recruiting |
NCT06109389 -
The Efficacy Of Lidocaine Infusion IN Chronic Unilateral Migraine Headache
|
Phase 2 | |
| Completed |
NCT04871581 -
Adjunctive Treatment of Chronic Migraine Using an Oral Dental Device
|
N/A | |
| Withdrawn |
NCT01749423 -
A Retrospective Study to Evaluate the Effectiveness of onabotulinumtoxinA in Preventing Headaches in Patients With Chronic Migraines
|
N/A | |
| Terminated |
NCT04349176 -
Onabotulinum Dose Comparison in Chronic Migraine Superior to 100 Units?
|
Phase 3 | |
| Completed |
NCT05381129 -
The Effect of Accompanying Temporomandibular Joint Dysfunction in Patients With Chronic Migraine
|
N/A | |
| Withdrawn |
NCT03465826 -
Developing a Mobile Health Pain-Coping Skills Training Program for the Treatment of Chronic Migraine: AIM 4
|
N/A | |
| Completed |
NCT05381012 -
Fibromyalgia Syndrome on Patients With Chronic Migraine
|
N/A | |
| Completed |
NCT05748535 -
Effect of Auricular Vagus Nerve Stimulation in Women With Migraine Disease
|
N/A | |
| Recruiting |
NCT05724771 -
COACT Study: CGRPmAbs + OnabotulinumtoxinA Assessment of Chronic Migraine Treatments Study
|
Phase 4 | |
| Recruiting |
NCT05313503 -
KETOMIGRAINE: Ketogenic Diet in Drug-resistant Chronic Migraineurs
|
N/A | |
| Recruiting |
NCT05079659 -
Rate , Predictors and Outcome of Chronic Migraine
|
||
| Completed |
NCT03698409 -
Onabotulinumtoxin Type A Reconstitution With Preserved Versus Preservative-free Saline in Chronic Migraine.
|
Phase 4 | |
| Completed |
NCT06118190 -
Mesotherapy in the Treatment of Chronic Migraine
|
N/A | |
| Completed |
NCT04017741 -
A Study Investigating the Efficacy of GON Blocks.
|
Phase 4 | |
| Completed |
NCT05679908 -
A Study to Evaluate the Efficacy and Safety of TNX-1900 in Patients With Chronic Migraine
|
Phase 2 |