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Clinical Trial Summary

The purpose of this study is to determine the maximum tolerated dose (MTD), recommended dose for expansion (RDFE), safety and tolerability of BGB-10188 as monotherapy in participants with relapsed/refractory (R/R) mature B-cell malignancies; in combination with zanubrutinib in participants with R/R follicular lymphoma (FL), R/R mantle cell lymphoma (MCL) or R/R diffuse large B-cell lymphoma (DLBCL); and in combination with tislelizumab in participants with advanced solid tumors.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04282018
Study type Interventional
Source BeiGene
Contact BeiGene
Phone 1-877-828-5568
Email clinicaltrials@beigene.com
Status Recruiting
Phase Phase 1/Phase 2
Start date May 25, 2020
Completion date December 31, 2025

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