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Brain Effects of Opiate Agonist and Antagonist

Chronic Low-back Pain Clinical Trial

Official title:
Brain Effects of Opiate Agonist and Antagonist

Clinical Trial Summary

This study will look at the short-term effect of morphine on brain response to food.

Clinical Trial Description

Chronic low back pain patients and healthy controls will be recruited for this study. Participants' brain will be scanned at baseline and then again on a different day after the administration of an oral dose of 30 mg morphine in an open label design. Participants will receive morphine 60 minutes prior to the start of the second scanning session. The brain scans will include structural scans, functional scans at rest and functional scans during the ingestion of a highly caloric drink. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04342130
Study type Interventional
Source University of Rochester
Contact
Status Completed
Phase Phase 4
Start date April 27, 2018
Completion date April 16, 2019
View Details
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