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Mindfulness and Chronic Low Back Pain

Chronic Low Back Pain Clinical Trial

Official title:
Brain Mechanisms Supporting Mindfulness-based Chronic Pain Relief

Clinical Trial Summary

The purpose of this study is to see if mindfulness, a form of mental training, or listening to a book alters brain activation in response to raising your leg that may produce the feeling of pain. A technique called functional magnetic resonance imaging (fMRI) allows scientists to determine which parts of the brain are active during a particular task. This study will provide new information about how mindfulness affects the brain.

Clinical Trial Description

To determine if mindfulness meditation-induced reductions in chronic low back pain (cLBP) patients will be associated with greater anterior insula (aINS), orbitofrontal cortex (OFC), subgenual anterior cingulate cortex (sgACC), and/or thalamic deactivation when compared to rest, the sham-mindfulness meditation and the book-listening control groups. One-hundred and twenty individuals will be randomized to a mindfulness meditation (n=40), non-mindfulness meditation (n=40) and book-listening-control (n=40). Each participants will be administered noxious heat and the chronic low back pain evoking, straight leg raise test during fMRI. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03354585
Study type Interventional
Source University of California, San Diego
Contact
Status Completed
Phase N/A
Start date January 2, 2020
Completion date February 5, 2024
View Details
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