Chronic Low Back Pain Clinical Trial
Official title:
Efficacy of a Classification Based 'Cognitive Functional Therapy' in Nurses With Non Specific Chronic Low Back Pain - a Series of Case-controls
A series of case-studies to explore the efficacy of classification based cognitive functional
physiotherapy according to the classification system proposed by Peter O'Sullivan in specific
nursing population with non specific chronic low back pain.
The investigators hypothesis was that treatment targeting the mechanisms behind the problem
from a multidimensional perspective would be effective to reduce pain, disability and
sick-leave.
Low back pain (LBP) is a common, recalcitrant and costly health problem, which limits
patients' daily activities. In 85% of the cases, LBP is classified as 'non-specific', which
means there is no clear underlying patho-anatomical/radiological abnormality. This subgroup
often gives rise to a chronic fluctuating problem. Although most cases of LBP resolve within
8 to 12 weeks, it may become chronic in up to 15% of patients. LBP constitutes an enormous
and growing medical and socio-economical problem for the modern society. Nursing has been
identified amongst the top professions at risk for occupational LBP, with lifetime prevalence
between 66%-82%. The impact of LBP for nurses includes time off work, increased risk of
chronicity, associated personal and economic costs and reduced nursing workforce efficiency.
Non Specific Chronic Low Back Pain (NSCLBP) is widely viewed as a multifactorial
biopsychosocial pain syndrome. It has been proposed by several authors that NSCLBP represents
a vicious cycle associated with different combinations of maladaptive; cognitive (negative
beliefs, fear avoidance behaviours, catastrophising, depression, stress, lack of pacing and
coping), physical (pain provocative postures, movement patterns and pain behaviours) and
lifestyle (inactivity, rest) behaviours that act to promote pain and disability. However a
recent systematic review suggests that this change in paradigm and the investigators new
understanding of NSCLBP has not resulted in clinical trials utilizing multidimensional
classification systems or targeted interventions based on the underlying mechanisms. In line
with this paradigm shift a novel multidimensional classification system has been developed
incorporating the biopsychosocial model, which subgroups patients based on their underlying
pain mechanism. Enabling a classification based interventions targetting the maladaptive
cognitive, physical and lifestyle behaviours associated with the disorder.
;
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03243084 -
Transcranial Alternating Current Stimulation in Back Pain- Pilot Sudy
|
N/A | |
Suspended |
NCT04735185 -
Stem Cells vs. Steroids for Discogenic Back Pain
|
N/A | |
Completed |
NCT03162952 -
RAND Center of Excellence for the Study of Appropriateness of Care in CAM
|
||
Completed |
NCT03240146 -
Pulsed Shortwave Therapy Treatment for Chronic Musculoskeletal Low Back Pain
|
N/A | |
Completed |
NCT05282589 -
Lumbopelvic Manipulation Effects on Fatigue in Chronic Low Back Pain Patients
|
N/A | |
Completed |
NCT03637998 -
Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain
|
N/A | |
Recruiting |
NCT02289170 -
Clinical Study to Evaluate the Safety and Efficacy of Heating and Cooling Combination Therapeutic Device(OCH-S100)
|
N/A | |
Active, not recruiting |
NCT01944163 -
The IMPACT of a Referral Model for Axial Spondyloarthritis in Young Patients With Chronic Low Back Pain
|
N/A | |
Completed |
NCT02231554 -
Feldenkrais vs Back School for Treating Chronic Low Back Pain: a Randomized Controlled Trial
|
N/A | |
Recruiting |
NCT02063503 -
Identification of Prognostic Indicators for Rehabilitation in Chronic Nonspecific Low Back Pain Patients
|
N/A | |
Terminated |
NCT01620775 -
MR(Magnetic Resonance) Imaging of Neurotransmitters in Chronic Pain
|
N/A | |
Completed |
NCT01704677 -
Lumbar Disc Prosthesis Versus Multidisciplinary Rehabilitation; 8-year Follow-up
|
N/A | |
Completed |
NCT01177280 -
Prevalence of Potential Cytochrome P450 Pharmacokinetic Incident Drug-Drug Interactions Among Chronic Low Back Pain Patients Taking Opioid Analgesics and Associated Economic Outcomes
|
N/A | |
Completed |
NCT01490905 -
A Double Blind Placebo Study to Determine the Effectiveness of Theramine on the Management of Chronic Back Pain
|
Phase 4 | |
Completed |
NCT01177241 -
Cytochrome P450 Pharmacokinetic DDIs Among Patients With Chronic Low Back Pain Taking Opioids
|
N/A | |
Completed |
NCT01177254 -
Exposure to Potential Cytochrome P450 Pharmacokinetic Drug-Drug Interactions Among Osteoarthritis Patients: Incremental Risk of Multiple Prescriptions
|
N/A | |
Completed |
NCT00984815 -
Safety Study of HZT-501 in Patients Who Require Long-Term Daily Non-steroidal Anti-inflammatory Drug Treatment
|
Phase 3 | |
Completed |
NCT00761150 -
Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
|
Phase 3 | |
Completed |
NCT00767806 -
A Study for Patient With Chronic Low Back Pain
|
Phase 3 | |
Completed |
NCT00763321 -
Study to Evaluate the Safety and Efficacy of ABT-712 in Subjects With Moderate to Severe Chronic Low Back Pain (CLBP)
|
Phase 3 |