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Genetic Polymorphisms of Interleukin-10 and TNF-α on Outcome of HCV-Related Chronic Liver Disease

Chronic Liver Disease Clinical Trial

Clinical Trial Summary

The prognosis of chronic hepatitis C virus (HCV)infeciton varies from minimal progressive disease to cirrhosis or hepatocellular carcinoma. Host genetic factors contribute to disease severity. It is known that cytokine gene (including tumor necrosis factor-alpha (TNF-alpha) and interleukin-10 (IL-10) polymorphism affect disease prognosis.This study aims to assess the effect of TNF-alpha and IL-10, and their interaction,on prognosis of HCV-related chronic liver disease

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Intervention Model: Factorial Assignment, Masking: Open Label

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00630006
Study type Interventional
Source Kaohsiung Medical University Chung-Ho Memorial Hospital
Contact Jen-Eing Jeng, M.D.
Phone 886-7-3121101
Email jejeng@cc.kmu.edu.tw
Status Recruiting
Phase N/A
Start date January 2007
Completion date December 2008
View Details
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