Effects of iCBT & Exercise for Chronic Knee Patients

Status Not yet recruiting

Clinical Trial Summary

The goal of this clinical trial is to study the effects of using an internet-based cognitive behavioural therapy (iCBT) program and exercise in chronic knee patients with psychological distress. The main question[s] it aims to answer are: - What are the effects of a combined iCBT and standardized exercise program on pain and function in chronic knee pain patients with psychological distress - What are the effects of a combined iCBT and standardized exercise program on depression, psychological distress, physical function, quality of life, and quadriceps muscle strength in chronic knee pain patients with psychological distress - Do a combined iCBT and standardized exercise program significantly improve pain and function in chronic knee pain patients with psychological distress compared to a control group? - Do a combined iCBT and standardized exercise program significantly improve depression, psychological distress, physical function, QoL, and quadriceps muscles strength in chronic knee pain patients with psychological distress compared to a control group? Participants will be allocated randomly to either intervention group or control group. Intervention group will be given iCBT, exercise and educational program, while the control group will be given exercise and educational program only. Researchers will compare both groups to see if the intervention group improves much better in terms of pain, function and other outcome measures compared to the study group.

Clinical Trial Description

This will be a 2-arm quasi-randomized controlled trial of eight weeks of intervention involving eight sessions of standardized exercise program and either concomitant iCBT and educational sessions or educational sessions only. Measurements will be taken at baseline and eight weeks immediately following the intervention. Primary outcome measures are a numerical pain rating scale, 40-m Fast-Paced Walk Test, Step Test, and 30 seconds Chair Stand Test. Secondary outcome measures are Patient Health Questionnaire, Psychological Distress, Knee Injury and Osteoarthritis Outcome Score Physical Function Short Form, Health-Related Quality of Life-Short Form-12, and Quadriceps Maximum Isometric Muscle Strength. ;

Study Design

Related Conditions & MeSH terms

Chronic Knee Pain

Clinical Trial Details

NCT number	NCT06133738
Study type	Interventional
Source	University of Bahrain
Contact	Amal Alaradi, MSc
Phone	+97336366300
Email	to.alaradi@gmail.com
Status	Not yet recruiting
Phase	N/A
Start date	December 1, 2023
Completion date	March 1, 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05920382` - Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain.	N/A
Active, not recruiting	`NCT06340035` - Percutaneous Peripheral Nerve Stimulation of Gluteus Nerves to Improve Hip Strength and Power	N/A
Recruiting	`NCT05473663` - Radiofrequency Ablation After Total Knee Arthroplasty	N/A
Withdrawn	`NCT05335486` - Investigating RELEARN Neurofeedback as Treatment for Chronic Musculoskeletal Pain	Phase 2/Phase 3
Completed	`NCT05031104` - Low-energy Laser Applications in Patients With Juvenile Idiopathic Arthritis	N/A
Not yet recruiting	`NCT06000709` - Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections	Phase 4
Completed	`NCT05003323` - Brain Biomarker of Endogenous Analgesia in Patients With Chronic Knee Pain
Recruiting	`NCT04580732` - Clinical Trial of the MiniStim PNS for Knee Pain- "FLEX" Study	N/A
Terminated	`NCT04601168` - Assessment of the Safety and Performance of a Compression Knee Support in the Prevention of Injuries During Sports Practice
Completed	`NCT01977872` - JointADventure: A Worksite Activity-Diet Intervention for Chronic Knee Pain	N/A
Recruiting	`NCT05407610` - Comparison of Conventional and Cooled Radiofrequency of the Genicular Nerves in Patients With Chronic Knee Pain	N/A
Recruiting	`NCT05816798` - Photobiomodulation in Chronic Knee Pain in Patients Who Are in PreRehabilitation for Bariatric Surgery	Phase 2/Phase 3
Terminated	`NCT04275128` - Cooled Versus Conventional Genicular Radiofrequency Ablation for Chronic Knee Pain
Completed	`NCT04234984` - Patients With Chronic Knee Pain Treated With Conventional Radiofrequency of the Genicular Nerves
Completed	`NCT05315934` - Comparing the Effects of Upper and Lower Body Aerobic Exercise on Pain in Individuals With Chronic Knee Pain	N/A
Completed	`NCT02931435` - Radiofrequency For Chronic Knee Pain Post-Arthroplasty	N/A
Completed	`NCT05137080` - Dexamethasone and Functional Outcome After TKA	Phase 4
Recruiting	`NCT05251142` - Plyometric Training in Volleyball Players With Chronic Knee Pain	N/A
Recruiting	`NCT06004882` - Peripheral Nerve Stimulation of Genicular Nerves Versus Conventional Therapy With Intra-articular Steroid Injection for Chronic Knee Pain: A Prospective, Randomized Pilot Study	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Effects of iCBT and Exercise for Chronic Knee Patients — iCBT

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms