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Acute Equol Supplementation and Vascular Function in Women With and Without CKD

Chronic Kidney Diseases Clinical Trial

Official title:
Acute Equol Supplementation and Vascular Function in Postmenopausal Women With and Without CKD

Clinical Trial Summary

The risk of cardiovascular disease (CVD) is significantly elevated in patients with chronic kidney disease (CKD). Notably, women with CKD commonly experience menstrual disturbances induced by CKD, which may contribute to impaired vascular function and elevated CVD risk. However, most of the literature in nephrology focuses on male patients, and studies on women's vascular health are limited. Establishing effective therapies for improving vascular function and reducing CVD risk in women with CKD is a high research priority of the NIH. Equol contributes to improvement in vascular function, mediated in part by its anti-oxidative and anti-inflammatory properties. However, there is no information on the effect of equol on vascular function in women with CKD. The goal of the proposed project is to determine the acute effect (1 hour after ingestion) of oral equol supplementation on vascular function in postmenopausal women with and without CKD.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06128278
Study type Interventional
Source University of Colorado, Denver
Contact Ester Oh
Phone 303-724-3765
Email ester.oh@cuanschutz.edu
Status Recruiting
Phase Phase 2
Start date March 7, 2023
Completion date March 31, 2025
View Details
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