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NCT05550467 Clinical Trial

24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease

Chronic Kidney Diseases Clinical Trial

Official title:
24-hour Urinary Electrolyte Excretion and Renal Prognosis in Chronic Kidney Diseaseļ¼ša Retrospective Cohort Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05550467
Other study ID # 2015BAI12B06-03
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2014
Est. completion date July 31, 2022

Study information
Verified date September 2022
Source Chinese PLA General Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Association between excretion pattern and development trajectory of urinary electrolytes (urine sodium, urine potassium, urine chlorine, urine magnesium, urine calcium, urine phosphorus, urine creatinine, urea, uric acid, urine glucose, urine protein, urine retinol) and adverse prognosis in patients with chronic kidney disease

Recruitment information / eligibility
Status Completed
Enrollment 10000
Est. completion date July 31, 2022
Est. primary completion date July 30, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria: - Our study is a retrospective cohort study. The study included patients with adult(Age=18years)CKD who were hospitalized in the Department of Nephrology, First Medical Center of Chinese PLA General Hospital from January 2014 to July 2022. Patients with CKD who had one or more 24-hour urinary electrolyte excretion tests at intervals of more than three months were included in the subgroup analysis. Exclusion Criteria: - Patients with hemodialysis therapy and urine volume less than 500ml were excluded.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
Chinese PLA General Hospital

Outcome
Type Measure Description Time frame Safety issue
Primary Kidney disease progression eGFR decline > 50%; dialysis; kidney transplant 2014.1.1-2022.7.31
Primary Death All cause death 2014.1.1-2022.7.31
Secondary Cardiovascular disease myocardial infarction, angina pectoris, stable heart failure, peripheral artery disease , revascularization, cerebrovascular events 2014.1.1-2022.7.31
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