24-hour Urinary Electrolyte Excretion in Chronic Kidney Disease

Chronic Kidney Diseases Clinical Trial

Official title:

24-hour Urinary Electrolyte Excretion and Renal Prognosis in Chronic Kidney Disease：a Retrospective Cohort Study

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05550467
• Other study ID #: 2015BAI12B06-03
• Status: Completed
• Start date: January 1, 2014
• Est. completion date: July 31, 2022

Study information

• Verified date: September 2022
• Source: Chinese PLA General Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Association between excretion pattern and development trajectory of urinary electrolytes (urine sodium, urine potassium, urine chlorine, urine magnesium, urine calcium, urine phosphorus, urine creatinine, urea, uric acid, urine glucose, urine protein, urine retinol) and adverse prognosis in patients with chronic kidney disease

Recruitment information / eligibility

• Status: Completed
• Enrollment: 10000
• Est. completion date: July 31, 2022
• Est. primary completion date: July 30, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

Inclusion Criteria:

• Our study is a retrospective cohort study. The study included patients with adult(Age=18years)CKD who were hospitalized in the Department of Nephrology, First Medical Center of Chinese PLA General Hospital from January 2014 to July 2022. Patients with CKD who had one or more 24-hour urinary electrolyte excretion tests at intervals of more than three months were included in the subgroup analysis.

Exclusion Criteria:

• Patients with hemodialysis therapy and urine volume less than 500ml were excluded.

Related Conditions & MeSH terms

• Chronic Kidney Diseases
• Electrolyte Imbalance
• Kidney Diseases
• Renal Insufficiency, Chronic

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Chinese PLA General Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Kidney disease progression	eGFR decline > 50%; dialysis; kidney transplant	2014.1.1-2022.7.31
Primary	Death	All cause death	2014.1.1-2022.7.31
Secondary	Cardiovascular disease	myocardial infarction, angina pectoris, stable heart failure, peripheral artery disease , revascularization, cerebrovascular events	2014.1.1-2022.7.31