Uremic Toxins and Outcomes in Chronic Kidney Disease

Chronic Kidney Diseases Clinical Trial

Official title:

The Association Between Uremic Toxins and Outcomes and Comorbidities in Patients With CKD

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03711617
• Other study ID #: CKD-toxins
• Status: Recruiting
• Start date: May 1, 2018
• Est. completion date: December 31, 2024

Study information

• Verified date: November 2023
• Source: Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
• Contact: Feng Ding, PhD
• Phone: 86-21-53315165
• Email: dingfeng[@]sjtu.edu.cn
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this cohort study is:

To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.

Description:

To investigate the etiology and epidemiology of comorbidities in CKD; To find out risk factors associated with the mortality of CKD; To find out uremic toxins which are related to the mortality and comorbidities of CKD; To focuse on the association between uremic toxins and inflammation, oxidative stress and nutritional status in CKD.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 500
• Est. completion date: December 31, 2024
• Est. primary completion date: December 31, 2024
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• age =18 years old;

• clinically diagnosed with chronic kidney disease, according K/DOQI criteria.

Exclusion Criteria:

• acute kidney injury

• history of kidney injury <3 months

• malignancy

• pregnancy

• incomplete clinical data

Related Conditions & MeSH terms

• Chronic Kidney Diseases
• Kidney Diseases
• Renal Insufficiency, Chronic

Locations

Country	Name	City	State
China	Shanghai Ninth People's Hospital	Shanghai	Shanghai

Sponsors (1)

Lead Sponsor	Collaborator
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	all cause mortality		5 years
Secondary	comorbidities		5 years