Chronic Kidney Disease Clinical Trial
— SLIMMOfficial title:
Sit Less, Interact, Move More (SLIMM) Intervention for Sedentary Behavior in Chronic Kidney Disease (CKD)
Verified date | September 2019 |
Source | University of Utah |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Sedentary behavior is engaging in activities in the seated or lying position that barely
raise the energy expenditure level and has emerged as an important risk factor for obesity,
diabetes, cardiovascular disease and mortality.
The primary hypothesis is that the Sit Less, Interact, Move More (SLIMM) intervention in
Chronic Kidney Disease (CKD) will be effective in decreasing sedentary duration by increasing
casual walking duration and thereby, increase physical activity energy expenditure.
Status | Completed |
Enrollment | 106 |
Est. completion date | September 12, 2019 |
Est. primary completion date | September 12, 2019 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Stage 3/4 Chronic Kidney Disease, as defined by estimated glomerular filtration rate (eGFR) 15 to < 60 ml/min/1.73m^2 - Body Mass Index (BMI): 25 to 39.9 kg/m^2 - Able to achieve gait speed of > 1 m/sec and able to walk = 320 meters in the 6-minute walk test Exclusion Criteria: - Previous renal replacement therapy - Life expectancy < 1 year - Pregnancy - Prison incarceration |
Country | Name | City | State |
---|---|---|---|
United States | University of Utah | Salt Lake City | Utah |
Lead Sponsor | Collaborator |
---|---|
Srinvasan Beddhu | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) |
United States,
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* Note: There are 69 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in Sedentary Activity Duration | Change in sedentary activity duration (average sedentary minutes per hour), as measured by a validated accelerometry monitor from baseline to 24 weeks | Baseline and 24 Weeks | |
Primary | Change in Casual Walking Duration | Change in casual walking activity duration (average walking minutes per hour), as measured by a validated accelerometry monitor from baseline to 24 weeks | Baseline and 24 Weeks | |
Secondary | Change in Waist Circumference | Change in waist circumference, measured in centimeters, from baseline to 24 weeks | Baseline and 24 Weeks | |
Secondary | Change in Non-Exercise Activity Thermogenesis | Change in non-exercise activity thermogenesis, measured in kilocalorie/kilogram/hour, from baseline to 24 weeks | Baseline and 24 Weeks | |
Secondary | Change in Physical Function | Change in walking distance, measured in meters, using the 6-minute walk test from baseline to 24 weeks | Baseline and 24 Weeks |
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