Oral Calcitriol for Reduction of Mild Proteinuria in Patients With CKD

Status Not yet recruiting

Clinical Trial Summary

The safety and efficacy of Caltriol on mild proteinuria (<1.0g/d) reduction in CKD patients.

Clinical Trial Description

Proteinuria is not only a capital sign of kidney disease, but also a marker of chronic kidney disease (CKD) progression. Emerging evidence in patients with CKD show that vitamin D and its analogs can reduce proteinuria or albuminuria in the presence of angiotensin-converting enzyme inhibithion. While some of the studies reported that vitamin D receptor activation has been associated with increased serum creatinine and reduced estimated glomerular filtration rates. Therefore, the investigators plan to conduct a randomized clinical study to evaluate the efficacy and safety of Calcitriol in the treatment of mild proteinuria (<1.0g/d) CKD patients,which has no specific treatment at present. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01820832
Study type	Interventional
Source	Huashan Hospital
Contact	Jing Chen, M.D. PhD
Phone	86-21-52889387
Email	chenjing1998@fudan.edu.cn
Status	Not yet recruiting
Phase	Phase 4
Start date	March 2013
Completion date	June 2015

View Details

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