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Clinical Trial Summary

Ezetimibe possesses pharmacophore features to inhibit NTCP, the receptor required for HBV and HDV hepatocyte entry that include two hydrophobes and one hydrogen bond acceptor. Therapy with Ezetimibe may lead to decline in hepatitis D virus levels. The aim of the study is to evaluate the utility of Ezetimibe in patients with chronic HDV infection


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03099278
Study type Interventional
Source Ziauddin Hospital
Contact Zaigham Abbas
Phone 922135862937
Email drzabbas@gmail.com
Status Recruiting
Phase Phase 2
Start date January 2017
Completion date October 2017

See also
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Completed NCT00001457 - Lamivudine for Chronic Hepatitis B Phase 2
Recruiting NCT06121427 - Incidence of Viral Hepatitis D Relapses Upon Discontinuation of Bulevirtide in Patients With Chronic Hepatitis D and Negative HDV RNA
Recruiting NCT05723068 - Burden of Hepatitis D Virus (HDV) Infection in Italy