Chronic Disease Clinical Trial
— MTOPOfficial title:
Trajectories of Chronic Multimorbidity Patterns in Patients >65 Years Old. MTOP
NCT number | NCT05717309 |
Other study ID # | CIR2021038 |
Secondary ID | |
Status | Completed |
Phase | |
First received | |
Last updated | |
Start date | February 10, 2022 |
Est. completion date | July 31, 2023 |
Verified date | August 2023 |
Source | Corporacion Parc Tauli |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
Following the MRisk-COVID project, MTOP (Multimorbidity Trajectories in Older Patients) study was developed. It is a retrospective observational study using Real World Data that aims to identify patterns of chronic multimorbidity in patients aged ≥65 years and their evolution and trajectories in the previous 10 years. The secondary objective is to identify the relationship between the trajectories of multimorbidity patterns in the previous 10 years and the severity of the infection by COVID-19.
Status | Completed |
Enrollment | 3988 |
Est. completion date | July 31, 2023 |
Est. primary completion date | January 17, 2023 |
Accepts healthy volunteers | |
Gender | All |
Age group | 65 Years to 94 Years |
Eligibility | Inclusion Criteria: - Positive results of COVID-19 laboratory tests - COVID-19 related clinical profile verified by healthcare professionals Exclusion Criteria: - Males >90 years (re-identification risk) |
Country | Name | City | State |
---|---|---|---|
Spain | Corporacio Parc Taulí | Sabadell | Barcelona |
Lead Sponsor | Collaborator |
---|---|
Corporacion Parc Tauli | Department of Health, Generalitat de Catalunya |
Spain,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Chronic multimorbidity patterns - Time Frame 1 | Obtained using fuzzy c-means cluster analysis | Baseline (2020) | |
Primary | Chronic multimorbidity patterns - Time Frame 2 | Obtained using fuzzy c-means cluster analysis | 5 years before (2015) | |
Primary | Chronic multimorbidity patterns - Time Frame 3 | Obtained using fuzzy c-means cluster analysis | 10 years before (2010) | |
Primary | Trajectories of chronic multimorbidity patterns | Obtained by assigning the highest probable cluster at each time point | Change over 10 years | |
Secondary | Severe COVID-19 infection | Severe COVID-19 infection was defined as the occurrence of at least one of the following conditions during any of the registered COVID-19 episodes: severe respiratory affection (including insufficiency, failure, or distress); use of respiratory support (including mechanical ventilation or oxygen therapy); septic shock; multiple organ failure (the combination of respiratory failure and any other organ failure); inflammatory response; admission to intensive care unit; and mortality | From 27-February-2020 to 15-June-2020 |
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