Cohort Study in South China

Chronic Disease Clinical Trial

Official title:

Prospective Cohort Study of Chronic Diseases in South China

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT03288805
• Other study ID #: 2017YFC0907100
• Status: Active, not recruiting
• Start date: January 1, 2017
• Est. completion date: December 31, 2030

Study information

• Verified date: May 2022
• Source: Sun Yat-sen University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Healthy Chinese residents from South China will be recruited and followed up for at least 4 years to evaluate the association between climate, diet and lifestyle and risks for the development of chronic diseases. Physical examination, questionnaire survey and biological sample collection will be conducted at baseline and the incidence of chronic diseases will be investigated during follow-up.

Description:

110,000 adult Chinese (35 to 74 years old) without chronic diseases and major disability who have been living in South China including Guangdong, Fujian, Guangxi and Hainan for more than 5 years will be recruited. All participants will be prospectively followed up for the incidence of chronic diseases (stroke, coronary heart disease, malignant neoplasms, chronic obstructive pulmonary diseases, diabetes and hypertension) and their risk factors (impaired glucose tolerance and obesity). Information about socio-demographic, diet, lifestyle, psychological status, medical history and current medication will be collected by questionnaires. Physical examinations including height, weight, waist and hip circumferences, blood pressure, fat mass and vital capacity will be conducted. Besides, blood, urine and fecal samples will be collected for further analysis. Annual meteorological data throughout the study period will also be collected. The associations between climate, diet and lifestyle and risks for chronic diseases will be evaluated.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 110000
• Est. completion date: December 31, 2030
• Est. primary completion date: December 31, 2030
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 35 Years to 74 Years

Eligibility

Inclusion Criteria:

• adult Chinese (35-74 years old) who have been living in South China including Guangdong, Fujian, Guangxi and Hainan provinces for more than 5 years.

Exclusion Criteria:

• any subject diagnosed with stroke, coronary heart disease, malignancy, chronic obstructive pulmonary disease, diabetes and hypertension.

• any subject who suffer from major disability and cannot participate in the study.

Related Conditions & MeSH terms

• Chronic Disease

Locations

Country	Name	City	State
China	Sun Yat-Sen University	Guangzhou	Guangdong

Sponsors (8)

Lead Sponsor	Collaborator
Min Xia	Fujian Medical University, Guangxi Medical University, Guangzhou Medical University, Guangzhou No.12 People's Hospital, Hainan Medical College, Shenzhen Fifth People's Hospital, The First Affiliated Hospital of Xiamen University

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Incidence of chronic disease	Incidence of chronic disease, including stroke, coronary heart disease, cancer, chronic obstructive pulmonary disease, diabetes and hypertension	4 years
Secondary	Risk factors for chronic diseases	Incidence of impaired glucose tolerance and obesity	4 years