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Chronic Disease clinical trials

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NCT ID: NCT04568382 Completed - Clinical trials for Diabetes Mellitus, Type 2

Diabetes Communication and Treatment Burden

Start date: October 12, 2020
Phase: N/A
Study type: Interventional

The objective of this proposal is to pilot test two types of pre-visit planning, where clinical staff reviews charts and talks to patients before their doctors appointments, to reduce the burden of diabetes care on the patient without increasing the visit workload during busy primary care clinics.

NCT ID: NCT04566107 Completed - Clinical trials for Multiple Chronic Conditions

Self-Management Interventions Using Mobile Health for the Multimorbid

Start date: October 14, 2019
Phase: N/A
Study type: Interventional

The purpose of this pilot study is to evaluate the feasibility and impact of delivering mobile health self-management interventions to improve adherence to the prescribed treatment in a multimorbid population returning home after hospital discharge.

NCT ID: NCT04556786 Completed - Chronic Disease Clinical Trials

A Pharmacist-led Transitions of Care Program

Start date: October 2, 2018
Phase: N/A
Study type: Interventional

This study was to show the value of pharmacists in providing transitions of care to and improving health outcomes of uninsured populations. It also aimed to demonstrate the feasibility of implementing a transitions of care program in an indigent care clinic with limited resources. We hypothesized that a pharmacist-led transitions of care program will reduce 30-day hospital readmission rates among the uninsured discharged from a community hospital.

NCT ID: NCT04552431 Completed - Clinical trials for Chronic Prostatitis With Chronic Pelvic Pain Syndrome

Chronic Prostatitis Collaborative Research Network Clinical Trial- Ciprofloxacin and Tamsulosin

CPCRN RCT1
Start date: September 30, 1997
Phase: Phase 2
Study type: Interventional

Although the cause of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is unknown, physicians sometimes try to treat it with antibiotics or alpha-receptor blockers. In this multicenter, double-blind factorial trial, 196 men with moderately severe CP/CPPS were randomly assigned to 6 weeks of treatment with ciprofloxacin, tamsulosin, both drugs, or placebo. Neither ciprofloxacin nor tamsulosin substantively reduced symptoms. Ciprofloxacin and tamsulosin were not effective treatments for CP/CPPS. Patients had long-standing, refractory CP/CPPS and received trial treatments for only 6 weeks. Patients with new diagnoses who are given longer courses of the trial treatments might respond differently.

NCT ID: NCT04551703 Completed - Clinical trials for Chronic Rhinosinusitis (Diagnosis)

Adrenaline Solution Irrigation and Bleeding During Sinus Surgery

Start date: July 1, 2016
Phase: Phase 1
Study type: Interventional

Intranasal irrigation with normal saline is routinely used in sinus surgery to clean the tip of the nasal endoscope and clear the surgical field from blood. The purpose of this study is to evaluate the difference in the surgical visualization, surgeon satisfaction and total blood loss when intraoperative irrigation was performed with a solution of normal saline with adrenaline as compared to irrigation with normal saline alone in FESS.

NCT ID: NCT04536259 Completed - Chronic Disease Clinical Trials

Assessing People's Hospital Outpatient Appointment Preferences in the United Kingdom

Start date: September 11, 2020
Phase: N/A
Study type: Interventional

The sustainability of the United Kingdom's National Health Service's (NHS) is threatened immediately by Covid-19 and continually by an increasing prevalence of long-conditions that cannot be cured but can be maintained. Shifting traditional face-to-face outpatient appointments to remote video consultations may help the NHS continue to serve patients efficiently. While much research has examined healthcare providers' attitudes and beliefs about remote video consultations, less has attempted to understand how NHS service providers should invite patients to attend them. The present study examines how the framing of an invitation to attend a hospital outpatient appointment by video influences the proportion of people who agree to attend by video. It also explores some of the barriers and facilitators people may experience to attending appointments by video across diagnostic complexities and age groups. The results of this study should help hospitals better present patients with the option to attend video consultations where appropriate, and provide support to mitigate common barriers to people's willingness to give video consultations a go.

NCT ID: NCT04532073 Completed - Elderly Patients Clinical Trials

Sub-study of the Essen Study Centre for the ENTAiER Trial

Start date: July 27, 2021
Phase: N/A
Study type: Interventional

The present study is a sub-study of the ENTAiER study. The ENTAiER study is a multicenter, randomized, controlled study to evaluate the efficacy and safety of eurythmy therapy and Tai Chi in comparison to standard care in chronically ill older patients with an increased risk of falling. In addition to the main questions of the ENTAiER study, three additional questions are being investigated at the Hospital Essen-Steele: Proteome and telomere analyses as well as qualitative parameters are recorded and examined. The aim is to compare the changes in proteomes, telomeres and qualitative factors under eurythmy therapy, Tai Chi and standard care in chronically ill older patients with an increased risk of falling.

NCT ID: NCT04530968 Completed - Clinical trials for Disorder of Consciousness

Metabolic Abnormalities and Intestinal Microecology in Patients With Chronic Disorders of Consciousness

Start date: March 13, 2018
Phase:
Study type: Observational

Following severe traumatic brain injury, patients may remain unconscious for many years. It is the intestinal microbiome and metabolomics analysis comparing differentially intestinal microflora and metabolites between patients with chronic disorder of consciousness and controls so far. The investigators have mature data analysis technology. The obtained results provide new insight into understanding the molecular mechanisms underlying the chronic disorder of consciousness

NCT ID: NCT04518566 Completed - Clinical trials for Diabetes Mellitus, Type 2

Empowering Patients With Chronic Disease Using Profiling and Targeted Feedbacks Delivered Through Wearable Device

EMPOWER
Start date: May 11, 2021
Phase: N/A
Study type: Interventional

Chronic diseases are the leading cause of deaths in Singapore. The rising prevalence in chronic diseases with age and Singapore's rapidly aging population calls for new models of care to effectively prevent the onset and delay the progression of these diseases. Advancement in medical technology has offered new innovations that aid healthcare systems in coping with the rapid rising in healthcare needs. These include mobile applications, wearable technologies and machine learning-derived personalized behaviorial interventions. The overall goal of the project is to improve health outcomes in chronic disease patients through delivering targeted nudges via mobile application and wearable to sustain behavioral change. The objective is to design, develop and evaluate an adaptive interventional platform that is capable of delivering personalized behavioral nudges to promote and sustain healthy behavioral changes in senior patients with diabetes. The aim is to assess the clinical effectiveness of real-time personalized educational and behavioral interventions delivered through wearable (FitBit) and an in-integrative mobile application in improving patient activation scores measured using the patient activation measure (PAM). Secondary outcome measures include cost-effectiveness, quality of life, medication adherence, healthcare cost, utilization and lab results. Together with the experts from the SingHealth Regional Health System and National University of Singapore, the investigators will conduct a randomized controlled trial of 1,000 eligible patients. This proposal aims to achieve sustainable and cost-effective behavioral change in diabetes patients through patient-empowerment and targeted chronic disease care.

NCT ID: NCT04503954 Completed - Schizophrenia Clinical Trials

Efficacy of Chronic Disease Self-management Program in People With Schizophrenia

Start date: September 7, 2020
Phase: N/A
Study type: Interventional

This was a randomized controlled behavioral intervention trial to assess the efficacy of investigating program of chronic disease self-management program in people on schizophrenia patients conditions of depression, activities of daily living, social function, work, and quality of life.