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Chronic Disease clinical trials

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NCT ID: NCT00464373 Terminated - Prostatitis Clinical Trials

Botulinum Toxin Type A for the Treatment of Male Chronic Pelvic Pain Syndrome

BTX-URO-01
Start date: April 2007
Phase: Phase 3
Study type: Interventional

The aim of this randomized placebo-controlled study is to demonstrate the efficiency and safety of the injection of Botulinum Toxin Type A (200 Units) into the external urethral sphincter for the treatment of chronic prostatitis/chronic pelvic pain.

NCT ID: NCT00430300 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

Safety And Efficacy Of UK-432,097 In Chronic Obstructive Pulmonary Disease.

Start date: January 2007
Phase: Phase 2
Study type: Interventional

Safety and efficacy (measured by spirometry) of UK-432,097 administration will be tested in patients with chronic obstructive pulmonary disease.

NCT ID: NCT00399373 Terminated - Chronic Illness Clinical Trials

Structuring the Integration of Care Management Services For Medicaid Enrollees Recipients With Chronic Illness, Substance Abuse Problems and Possible Psychiatric Disorders

Start date: November 2005
Phase: N/A
Study type: Observational

The study seeks to measure the effect of increased coordination of care on medical costs, treatment utilization and selected clinical indicators among a Medicaid population with chronic medical conditions and substance abuse problems? We shall address this question by conducting a demonstration project consisting of the provision of integrated care management (somatic and behavioral) to Medicaid enrollees living on the Eastern Shore of Maryland and who have both chronic medical conditions and problems with substance abuse. A specific component of the study will be the participation of Maryland's Mental Health Administration (MHA) and MAPS, the administrator of psychiatric services for the Medicaid enrollees in Maryland. We shall compare the results of the integrated care management for the study sample on the Eastern Shore with a control group from the counties of western Maryland.

NCT ID: NCT00394485 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

Tiotropium + Procaterol vs Tiotropium + Placebo in COPD Patients

Start date: May 2006
Phase: Phase 4
Study type: Interventional

Study compares the efficacy and safety of tiotropium + a beta agonist (procaterol) vs. tiotropium alone among patients with moderate chronic obstructive pulmonary disease

NCT ID: NCT00346749 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

ADVAIR DISKUS® (Fluticasone Propionate/Salmeterol) Inhaler Versus SEREVENT DISKUS® (Salmeterol) Inhlaer On Inflammatory Cells And Markers In Chronic Obstructive Pulmonary Disease. ADVAIR DISKUS® and SEREVENT DISKUS® Inhalers Are Trademarks of the GSK Group of Companies.

Start date: December 2006
Phase: Phase 4
Study type: Interventional

This study evaluates the effect of two medicines on COPD (Chronic Obstructive Pulmonary Disease). The study will last 12 weeks. At the end of 12 weeks of treatment, subjects will stop the study medicines for 2 weeks. The study will involve 6 visits to the clinic. Subjects who elect to undergo bronchoalveolar lavage (BAL) procedures will have 8 study visits. Subjects will give sputum, blood, and in some cases BAL samples. Subjects will have breathing tests and will complete diary cards during the study. All study medicines and examinations will be given at no cost to the study subjects. Both medicines used in this study have been approved by the US FDA.

NCT ID: NCT00301405 Terminated - Pelvic Pain Clinical Trials

Open-Label Study of Thalidomide for Chronic Prostatitis/Chronic Pelvic Pain

Start date: March 2006
Phase: Phase 2
Study type: Interventional

To determine the efficacy of thalidomide for treatment of the Chronic Pelvic Pain Syndrome (CPPS).

NCT ID: NCT00263874 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

Phase 2 Study of the Safety and Efficacy of UK-500,001 in Adult Patients With COPD

Start date: November 2005
Phase: Phase 2
Study type: Interventional

This initial proof of concept, phase II study aims to assess the safety and efficacy of UK-500,001 for the chronic maintenance treatment of adults with Chronic Obstructive Pulmonary Disease.

NCT ID: NCT00260598 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

LIFE-Lung Bronchoscopy in Patients at Risk for Developing Lung Cancer

Start date: August 1998
Phase: Phase 2
Study type: Interventional

The purpose of the study is to evaluate the usefulness and accuracy of the "LIFE-Lung Bronchoscopy" to identify early changes in lung tissues that show precancerous, cancer in situ (just beginning and not spread) and microscopic invasive cancer lesions versus the ability of the standard "White Light Bronchoscopy" to identify the same. This will be done as a part of routine monitoring bronchoscopy. Patients who have had a surgical resection of non-small cell lung cancer (NSCLC) and with no current evidence of disease (NED) will be eligible. Also eligible are patients who have had head or neck squamous cell carcinoma with radical head and/or neck dissection and who are currently NED. Patients with severe chronic, obstructive, pulmonary disease shown by pulmonary function testing abnormalities will also be eligible. In addition to the specialized bronchoscopy, doctors will be investigating the use of imaging spectroscopy. This is using an optical (visualizing) procedure to measure the light reflected back from tissue. Different lesions and normal tissues reflect light differently and in specific color wavelengths. By using measurements over time (different examinations/bronchoscopies) very small changes can be seen. This may allow eventually for very early diagnosing of precancerous or cancer in situ lesions, allowing for earlier treatment.

NCT ID: NCT00185523 Terminated - Leukemia Clinical Trials

Allogeneic Transplantation for Patients With Acute Leukemia or Chronic Myelogenous Leukemia (CML)

Start date: May 2002
Phase: Phase 2
Study type: Observational

The purpose of the study is to evaluate the overall and disease free survival of recipients who have received G-CSF mobilized stem cells from HLA matched sibling donors.

NCT ID: NCT00132730 Terminated - Clinical trials for Pulmonary Disease, Chronic Obstructive

An Investigational Drug Study In Patients With COPD (Chronic Obstructive Pulmonary Disease) (MK-0873-005)

Start date: June 1, 2004
Phase: Phase 2
Study type: Interventional

This is a study to evaluate the effectiveness and tolerability of a once-daily oral medication (MK-0873) for the treatment of COPD (chronic obstructive pulmonary disease) to determine whether the study drug leads to an improvement in pulmonary (lung) function, as well as symptoms, and quality of life.