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Sphenopalatine Ganglion Nerve Block vs. Elavil for Treatment of Transformed Migraines

Chronic Daily Headache Clinical Trial

Official title:
A Comparison of the Efficacy of 5% Lidocaine Anesthetic to Provide SPGB Vs. Elavil for the Treatment of Transformed Migraine

Clinical Trial Summary

This study will compare a local anesthetic technique that has been used to treat subjects suffering from transformed migraines (chronic migraines) versus medical management with traditional antidepressant Amitriptyline / Elavil. Subjects will be randomized into one of two treatment groups to compare the safety and efficacy of the therapies. Subjects will recieve either sphenopalatine ganglion nerve block with 5% lidocaine gel into the nasopharynx or medical management with traditional antidepressants, Elavil, to produce a reduction in the frequency and severity of the headache. We propose that there will be a difference in the outcomes when comparing the two methods of treating transformed migraines and that one research arm will result in more patient satisfaction and greater efficacy in the treatment of subjects

Clinical Trial Description

Arm one will receive Sphenopalatine Ganglion Nerve Block weekly for 4 weeks Arm two will receive Amitriptyline / Elavil daily for 30 Days ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02090998
Study type Interventional
Source Rutgers, The State University of New Jersey
Contact
Status Terminated
Phase Phase 4
Start date May 2014
Completion date March 16, 2020
View Details
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