Sacral Neuromodulation as Treatment for Chronic Constipation

Status Recruiting

Clinical Trial Summary

The objective of this study is to study if low level laser therapy will do more good than harm for patients with severe chronic refractory constipation. It is a proof of concept study without a placebo arm.

Clinical Trial Description

Patients will be offered the therapy if High-Resolution Colonic Manometry has shown that coordination between colon motility and recto-anal activity is abnormal and that autonomic nervous system assessment suggests a dysfunction of communication between the spinal cord autonomic nerves and the colon-rectum-anus. The therapy consists of a 3 week treatment with a total of 8 sessions of low level laser therapy. Effects will be assessed using symptom and quality of life questionnaires and physiological assessments of colon and pelvic floor function, at 4 weeks and 12 weeks. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03819062
Study type	Interventional
Source	McMaster University
Contact	Jihong Chen, MD PhD
Phone	2263439909
Email	chen338@mcmaster.ca
Status	Recruiting
Phase	N/A
Start date	September 8, 2019
Completion date	February 1, 2027

View Details

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