Chronic Anemia Clinical Trial
Official title:
The Effect of Chronic Anemia on Safety Period of Tracheal Intubation in Gynecology Patients
1. Every individual receiving a general anesthetic is at potential risk for developing a
''cannot intubate-cannot ventilate'' situation following anesthetic induction.
2. Building up of oxygen reserves assumes great significance as this provides a longer
duration of non-hypoxic apnea should one be faced with an unanticipated difficult
airway.
3. The main physiological functions of red blood cell hemoglobin are to deliver oxygen to
the peripheral tissues.
4. During anemia, a reduction in blood oxygen content occurs as a result of reduced Hb
while arterial oxygenation and oxyhemoglobin saturation remain high.
5. Previous studies about the duration of non-hypoxic apnoea focus on methods to improve
the safety period of tracheal intubation.
6. To our knowledge, there is no literature about the duration of non-hypoxic apnoea of
anemia patients.
7. The aim of this study was to assess the effect of chronic anemia on the duration of
non-hypoxic apnoea during induction of anaesthesia.
After breathing for 3 minutes, anesthesia induction was conducted. The endotracheal tube position was confirmed after anesthesia induction. Patients were left apneic with the endotracheal tube open to room air. The non-hypoxic apneic period was recorded as the time (in seconds) taken for the drop in pulse saturation to 90% or an apneic period of 10 min elapsed, whichever was earlier. ;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Health Services Research
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