Chromosomal Aneuploidies Clinical Trial
| Verified date | February 2021 |
| Source | Cervesi Hospital, Cattolica, Italy |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
The objective will focus on the characterization of DNA fragments present in Blastocoele fluid, and the evaluation of these fragments as potential target for Preimplantation Genetic Diagnosis. To reach this goal, real-time PCR, Whole Genome Amplification techniques and -subsequently- Next Generation Sequencing and aCGH approaches will be used.
| Status | Active, not recruiting |
| Enrollment | 35 |
| Est. completion date | January 2022 |
| Est. primary completion date | December 2021 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | Female |
| Age group | 18 Years to 40 Years |
| Eligibility | Inclusion Criteria: - IVF patient with supernumerary embryos to vitrify at blastocyst stage Exclusion Criteria: - IVF patient without blastocyst formation |
| Country | Name | City | State |
|---|---|---|---|
| Italy | Cervesi Hospital IVF Unit | Cattolica | Rimini |
| Lead Sponsor | Collaborator |
|---|---|
| Cervesi Hospital, Cattolica, Italy |
Italy,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Number of samples with DNA in blastocoele Fluid | the presence of DNA will be evaluated through rtPCR | 6 month | |
| Secondary | Number of euploid samples | Array CGH | 8 months |