Choroideremia Clinical Trial
Official title:
A Randomised, Open Label, Outcomes-Assessor Masked, Prospective, Parallel Controlled Group, Phase 3 Clinical Trial of Retinal Gene Therapy for Choroideremia Using an Adeno-Associated Viral Vector (AAV2) Encoding Rab Escort Protein 1 (REP1)
The objective of the study is to evaluate the efficacy and safety of a single sub-retinal injection of BIIB111 in participants with choroideremia (CHM).
This study was previously posted by NightstaRx Ltd. In October 2020, sponsorship of the trial was transferred to Biogen. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
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Choroideremia Gene Therapy Clinical Trial
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Phase 2 | |
| Completed |
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Phase 2 | |
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Phase 1/Phase 2 | |
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N/A | |
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Phase 1 | |
| Completed |
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Phase 2 | |
| Completed |
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N/A | |
| Completed |
NCT02341807 -
Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations
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Phase 1/Phase 2 | |
| Completed |
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N/A | |
| Enrolling by invitation |
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| Terminated |
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N/A |