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Choroidal Neovascularization clinical trials

View clinical trials related to Choroidal Neovascularization.

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NCT ID: NCT01880788 Completed - Clinical trials for Age Related Macular Degeneration

Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMD

Start date: November 2012
Phase: N/A
Study type: Observational

The study will be designed as a case control evaluation to compare the genetic profiles of three groups of patients categorized according to diagnosis. Group 1 - CNV secondary to CSC Group 2 - CSC without CNV Group 3 - CNV secondary to advanced AMD.

NCT ID: NCT01840410 Completed - Clinical trials for Choroidal Neovascularization (CNV)

Assess the Efficacy/Safety of Intravitreal Ranibizumab in People With Vision Loss Due to Choroidal Neovascularization.

Start date: September 2013
Phase: Phase 3
Study type: Interventional

To evaluate the efficacy and safety of 0.5 mg in adult patients with visual impairment due to choridal neovascularization (CNV).

NCT ID: NCT01810042 Completed - Clinical trials for Exudative Age-related Macular Degeneration

Indocyanine Angiographic Changes of Choroidal Neovascularization by Ranibizumab

Start date: October 2010
Phase: Phase 4
Study type: Interventional

Exudative age-related macular degeneration (ARMD) is complicated by choroidal neovascularization (CNV). Although anti-vascular endothelial growth factor treatment is the gold standard treatment, recurrence is the main limitation of the treatment. The changes of the CNV vascular structure is expected to provide information regarding recurrence. In the eyes that the vascular structure is clearly seen in indocyanine green angiography (ICGA), the vascular changes after ranibizumab injections will be investigated prospectively.

NCT ID: NCT01716026 Completed - Clinical trials for Choroidal Subfoveal/Juxtafoveal Neovascularization in High Myopia

Initial Treatment With Bevacizumab in Choroidal Neovascularization Associated to High Myopia

BENEMCOR
Start date: October 2012
Phase: Phase 3
Study type: Interventional

The purpose of this protocol is to determine wether the initial protocol in the treatment of subfoveal choroidal neovascularization associated to High Myopia with bevacizumab intravitreal injections is more effective when using 3 doses vs using 1 single dose in the load period

NCT ID: NCT01666821 Completed - Geographic Atrophy Clinical Trials

A Population-based Study of Macular Choroidal Neovascularization in a Chinese Population

Start date: May 2004
Phase: N/A
Study type: Observational

To investigate pathomorphological and functional variations of choroidal neovascularization (CNV) in age-related macular degeneration (AMD) in a Chinese population using optical coherence tomography (OCT) to find which kinds of Fundus characteristics indicated exudative AMD.

NCT ID: NCT01628354 Completed - Clinical trials for Choroidal Neovascularization

Study to Investigate the Safety and Efficacy of Ranibizumab in Patients With Choroidal Neovascularisation Due to Causes Other Than Age Related Macular Degeneration

Start date: February 2008
Phase: Phase 4
Study type: Interventional

The investigators hypothesize that it is safe and effective to treat patients with choroidal neovascularisation (abnormal blood vessels growing under the retina) secondary to causes other than age related macular degeneration (AMD) and pigment epithelial detachments (blisters of fluid under the retina) secondary to AMD with ranibizumab (Lucentis). These groups of patients have to date been excluded from the multicentre trials demonstrating significant benefit of Ranibizumab in the treatment of AMD.

NCT ID: NCT01578720 Completed - Clinical trials for Choroidal Neovascularization

Intravitreal Aflibercept Injection (IAI) for Presumed Ocular Histoplasmosis Syndrome

Start date: June 2012
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of intravitreal injection of aflibercept for the treatment of Choroidal Neovascularization (CNV) secondary to presumed ocular histoplasmosis syndrome (POHS).

NCT ID: NCT01570790 Completed - Clinical trials for Age-related Macular Degeneration

Combretastatin A4 Phosphate in Patients With Neovascular Age-Related Macular Degeneration

Start date: May 2003
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of the study is assess safety, bioactivity, and maximal tolerated dose of repeated weekly intravenous infusion of combretastatin A-4 phosphate (CA4P) in patients with neovascular age-related macular degeneration

NCT ID: NCT01570608 Completed - Clinical trials for Age Related Macular Degeneration

Lucentis KAV Study

Start date: March 2007
Phase: Phase 3
Study type: Interventional

Ranibizumab has been proven to be effective in large multicentre studies. However, the injections have to be repeated monthly. A combined therapy with the established photodynamic therapy might even be more effective, less intravitreal injections might be necessary due to a synergistic effect. The study will be conducted to explore whether intravitreal ranibizumab in monotherapy or in combination with verteporfin photodynamic therapy under a new time regime is an effective, safe and convenient treatment for patients with subfoveal Choroidal Neovascularisation (CNV) secondary to Age-Related Macular Degeneration (AMD).

NCT ID: NCT01527435 Completed - Clinical trials for Exudative Age-Related Macular Degeneration

Addition of 20mg/Day Zeaxanthin to Triple Therapy Treatment Options for Age Related Macular Degeneration (ARMD)

ARMD
Start date: December 2011
Phase: N/A
Study type: Observational

The purpose of this study is to evaluate the fact that 20 milligrams per day of oral Zeaxanthin as a supplement to patients with Choroidal neovascularization (CNV) and exudative age related macular degeneration (ARMD) undergoing combination therapy with intravitreal Bevacizumab (Avastin), intravitreal Dexamethasone and PDT laser photocoagulation and improves anatomic and visual outcome compared to patients not receiving oral Zeaxanthin. Study patients will be taking AREDS(PreserVision) and multivitamins (Centrum Silver); in addition one-half of the patients will receive 20mg of oral Zeaxanthin.