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Efficacy and Safety of Imatinib in Chordoma

Chordoma Clinical Trial

Official title:
Phase II Study of Imatinib Mesylate in Chordoma

Clinical Trial Summary

Preliminary response data, observed by Casali (Cancer, 2004) with imatinib 800 mg/day in patients affected by chordoma, need to be confirmed by a Phase II study, whose primary endpoint will be the formal assessment of clinical and pathological response. Aim of the study will be to explore treatment's activity, but also the potential impact of tumor response, the feasibility and outcome of subsequent surgery and radiotherapy. In addition, patterns of tumour response need to be investigated as well, given the peculiar patterns of response shown with molecular-targeted therapy in solid tumors.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00150072
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 2
Start date October 2004
Completion date April 2008
View Details
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