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Cholelithiasis clinical trials

View clinical trials related to Cholelithiasis.

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NCT ID: NCT02469935 Completed - Gallstones Clinical Trials

Accuracy of Surgeon-performed Ultrasound in Detecting Gallstones - a Validation Study

Start date: October 2011
Phase: N/A
Study type: Observational

Aims: To prospectively investigate the accuracy of surgeon-performed ultrasound for the detection of gallstones. Methods: 179 adult patients, with an acute or elective referral for an abdominal ultrasound examination, were examined with a right upper quadrant ultrasound scan by a radiologist as well as surgeon. The surgeons had undergone a four-week long education in ultrasound before participating in the study. Ultrasound findings of the surgeon were compared to those of the radiologist, using radiologist-performed ultrasound as reference standard.

NCT ID: NCT02461147 Completed - Cholecystitis Clinical Trials

Prospective Validation of "Cholecystectomy First" Strategy for Gallstone Migration

Start date: September 2013
Phase:
Study type: Observational

Initial cholecystectomy with intraoperative cholangiogram, followed if required by ERCP, has been implemented at the investigators institution as the standard management strategy for patients at intermediate risk of common bile duct stone migration, following a randomized controlled trial previously published by the same investigators team. The aim of this study is to prospectively analyze the outcomes of this strategy.

NCT ID: NCT02375529 Completed - Cholelithiasis Clinical Trials

A Trial of Single Incision Versus Four Ports Laparoscopic Cholecystectomy

Start date: May 2011
Phase: N/A
Study type: Interventional

Background: Single-incision laparoscopic cholecystectomy (SILC) is increasingly being used as a minimally invasive surgery with potential benefits over 4-port laparoscopic cholecystectomy (LC) in terms of postoperative pain and faster recovery. Methods: Seventy-three patients with symptomatic cholelithiasis were randomized to SILC (n=37) or LC (n=36). Data measures included operative details, adverse events, postoperative pain and analgesic requirements, success of the ambulatory process, return to normal activity and return to work, cosmetic results and quality of life score.

NCT ID: NCT02363699 Completed - Cholelithiasis Clinical Trials

Endovenous Lidocaine and Serum Cytokines Concentration

Start date: July 2013
Phase: Phase 4
Study type: Interventional

Ineffective treatment of postoperative pain may cause organic damage and chronic pain. Nevertheless, opioids, the leading drugs used for this purpose, present side effects that sometimes restrict their usability. In a multimodal context, new postoperative analgesia techniques have been developed focusing in the reduction of opioid use and their adverse effects, as well as postoperative chronic pain prevention. In this background, continuous intravenous infusion of lidocaine during perioperative period has shown to be promising. This trial aimed to compare postoperative analgesia, opioid consumption, duration of ileus and length of hospital stay and IL-1, IL-6, IL-10, α TNF and γ IFN levels in patients undergoing to laparoscopic cholecystectomies who received intravenous lidocaine in comparison to a control group. Intravenous lidocaine in the perioperative period of laparoscopic cholecystectomies was not able to reduce postoperative pain, opioid consumption, and duration of ileus or length of hospital stay. However, its anti-inflammatory effect was evidenced by the significant changes in the studied cytokines.

NCT ID: NCT02357589 Completed - Cholecystolithiasis Clinical Trials

3D vs 2D HD Laparoscopy in Cholecystectomy

Start date: January 2015
Phase: N/A
Study type: Interventional

The 3D-systems have emerged also to the world of surgery, and the three-dimensional laparoscopic systems are gradually entering the operating rooms. In the normal laparoscopy there are only two-dimensional view, which is somewhat challenging when operating in three-dimensional environment. Even though the 3D-systems have been widely studied in laboratory circumstances, there are still no evidence of benefits of 3D vs 2D in clinical point of view and no prospective randomized trials have been published. Therefore, the purpose of this study is to investigate is there something to gain in changing into 3D laparoscopic system for cholecystectomy (LCC).

NCT ID: NCT02351492 Completed - Gallstone Disease Clinical Trials

Radiological Investigation of Bile Duct Obstruction

RIBO
Start date: May 2015
Phase: N/A
Study type: Interventional

Patients with gallstone disease should be checked whether a common bile duct (CBD) stone could be present. In case of a certain suspicion for CBD stones further investigations should be performed. This can either be done by magnetic resonance cholangio-pancreaticography (MRCP) or by intraoperative cholangiography. The study investigates which pathway would be favorable in regard of an early hospital demission.

NCT ID: NCT02344654 Completed - Cholecystitis Clinical Trials

Fluorescence Cholangiography During Cholecystectomy - a RCT

Start date: May 1, 2015
Phase: N/A
Study type: Interventional

The primary objective is to compare the success rates of intraoperative fluorescent cholangiography using indocyanine green versus conventional X-ray cholangiography for the identification of bile duct anatomy during laparoscopic cholecystectomy for complicated gallstone disease in a randomized design with 120 patients.

NCT ID: NCT02327923 Completed - Gall Stone Disease Clinical Trials

Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy

Start date: January 2015
Phase: Phase 4
Study type: Interventional

Comparison of intraoperative infusion of lidocaine and esmolol in the postoperative requirement of opioid for postoperative pain management after laparoscopic cholecystectomy to decrease opioid related side effects and enhance postoperative recovery with multimodal analgesia approach.

NCT ID: NCT02317510 Completed - Polyp Clinical Trials

Combined Spinal Epidural Anesthesia and General Anesthesia for Laparoscopic Cholecystectomy

Start date: December 2014
Phase: N/A
Study type: Interventional

The aim of this study was to compare general anesthesia (GA) and combined (epidural and spinal) anesthesia (CA) for laparoscopic cholecystectomy. General anesthesia is a gold standard for laparoscopic cholecystectomy(LC). The use of combined anesthesia may offer several advantages over general anesthesia. Fifty patients will be randomly assigned to either the CA LC (25 patients) or GA LC (25 patients). All patients has symptomatic gall stone disease or polyp of gall bladder. Intraoperative events related to combined anesthesia , postoperative complications, pain score and duration of operation time will record.

NCT ID: NCT02185586 Completed - Gallbladder Polyp Clinical Trials

A Prospective Randomized Controlled Trial of Lower Abdominal Three-port Laparoscopic Cholecystectomy

Start date: May 2014
Phase: N/A
Study type: Interventional

We have designed a new method which could be used in laparoscopic cholecy- stectomy.Account to this new method, the three incisions are all located on the lower abdominal, theoretically it could get more beautiful outlook and less stress response than traditional laparoscopic cholecystectomy(two of the three incisions located on upper abdomen) or single port laparoscopic cholecystectomy(one large incision located on umbilicus). We plan to conduct a randomized controlled trial to compare those there methods of laparoscopic cholecystectomy, in order to find out if there will be some advantages of this new method,such as in lowering the stress response,reducing impact on respiration, relieving post-operation pain and improving appearance.