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Cholecystolithiasis clinical trials

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NCT ID: NCT04308993 Completed - Biliary Stones Clinical Trials

Percutaneous Endoscopic Biliary Exploration in Complex Biliary Stone Disease

Start date: January 1, 1999
Phase:
Study type: Observational

Patients with complex biliary stone disease are challenging to treat. The investigator present their experience in using urological interventions to treat challenging biliary stones. Methods: Fifteen patients with biliary calculi underwent 21 interventions using either extracorporeal shock wave lithotripsy (ESWL), percutaneous transhepatic choledochoscopy, percutaneous transcystic choledochoscopy, or a combination of these.

NCT ID: NCT04228835 Completed - Cholelithiasis Clinical Trials

Does ICG Fluorescence Cholangiography Identify Critical View of Safety Earlier in Laparoscopic Cholecystectomy

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

Achievement of critical view of safety (CVS) is recommended to reduce risk of hilar injury in laparoscopic cholecystectomy. Indocyanine green (ICG) fluorescence cholangiography, a novel technique of real time biliary visualization, is postulated to assist dissection during laparoscopic cholecystectomy (LC). However, its use in providing a faster and safer LC has yet to be established. The main objective of this study is to evaluate whether the use of ICG enhanced fluorescence cholangiography will help in earlier identification critical view of safety during LC.

NCT ID: NCT04213092 Completed - Clinical trials for Choledocholithiasis With Cholecystitis With Obstruction

Single Setting ERCP and Laparoscopic Cholecystectomy is a Safe Procedure in Patients With Cholecysto-Choledocholithiasis

Start date: November 2012
Phase:
Study type: Observational

The ideal management of cholecysto-choledocholithiasis is an open cholecystectomy (OC) with the common bile duct (CBD) exploration worldwide. The single setting 2-stage approach- endoscopic retrograde cholangiopancreatography (ERCP), endoscopic sphincterotomy (EST), and CBD clearance followed by laparoscopic cholecystectomy (LC) offers an advantage, mainly by reducing the hospital stay, the cost, and the morbidity. Investigators did a prospective study in patients admitted for the management of the cholecysto-choledocholithiasis in the Department of Surgery at the Lumbini Medical College and Teaching Hospital from November 2012- October 2015. They underwent 2-stage ERCP+LC in a single setting and investigators compared them with 2-stage OC+CBD exploration in a single setting approach. The patients with the open procedure were the investigator's control groups. All the included cases in the study were elective.

NCT ID: NCT04208568 Completed - Cholelithiasis Clinical Trials

Comparison of Postoperative Pain After Gallbladder Retrieval From Umbilical and Epigastric Ports.

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

To know the association of postoperative pain after gallbladder removal from umbilical port site versus epigastric portsite, after four ports laparoscopic cholecystectomy,and the epigastric port site was found to be friendly for the patients in terms of less pain after gallbladder removal from this site after surgery.

NCT ID: NCT04142203 Completed - Appendicitis Clinical Trials

Implementation of 23 Hour Surgery Model in a Tertiary Hospital

Herko
Start date: May 16, 2017
Phase:
Study type: Observational

Extended day surgery or 23 h surgery (23-hour surgery) is a surgical model where patients arrive to the hospital from home at the day of surgery, are operated and recover in a 23 h surgery unit. 23H surgery units are usually situated near postoperative recovery unit. THe 23 H surgical model was implemented in Kuopio University Hospital 2015 and between May 2017-May 2018 patients were recruited in the present prospective follow up cohort study. Patients were informed and they gave their informed consent. The patients were contacted two weeks after the study and details of their recovery were asked.

NCT ID: NCT04052633 Completed - Choledocholithiasis Clinical Trials

Success of Intraoperative Cholangiography

Start date: January 1, 2018
Phase:
Study type: Observational [Patient Registry]

The purpose of the present study was to evaluate the success of routine use of intraoperative cholangiography (IOC ) and to examine the factors that are hindering the performance of intraoperative c-arm cholangiography.

NCT ID: NCT04025645 Completed - Biliary Disease Clinical Trials

Common Bile Duct Pressures in Patients With and Without Cholelithiasis

Start date: January 1, 2015
Phase:
Study type: Observational

Objective. To measure the pressures of the common bile duct in patients with and without cholelithiasis and relating them to the presence of pancreatobiliary reflux. Summary Background Data. The reflux of pancreatic enzymes into the epithelium of the bile duct and mainly of the gallbladder is an abnormal phenomenon that plays a role in the lithogenesis and carcinogenesis of this epithelium. It has been suggested that the cause of this reflux is the dysfunction of the sphincter of Oddi. Because the pressure of the common bile duct depends on the pressures of the sphincter of Oddi, this dysfunction would be reflected in an increase in the pressure of the common bile duct in patients with cholelithiasis. Methods. A prospective case-control study was designed. The universe was constituted by a convenience sample in which all patients undergoing gastrectomy for gastric cancer during 30 months in our institution were included. The primary outcome measure was to establish differences between common bile duct pressures in patients with and without cholelithiasis. Results. Common bile duct pressures in patients with gallstones showed a significant elevation (Mean 16.9 mmHg) compared to those of patients without gallstones (Mean 3.3 mm Hg) (p<0.0001). These pressures correlated with the values of amylase and lipase in gallbladder bile; higher levels of these enzymes were found in patients with gallstones compared to patients without gallstones (p<0.0001). Conclusions. Common bile duct pressures in patients with cholelithiasis were significantly elevated above the parameters previously considered normal.

NCT ID: NCT03937037 Completed - Stone - Biliary Clinical Trials

Effect of Saline Irrigation in Reducing Choledocholithiasis Recurrence After ERCP

Start date: May 10, 2019
Phase: N/A
Study type: Interventional

In this prospective study, the investigators assessed the utility of intermittent saline irrigation in reducing the recurrent rate of choledocholithiasis after the endoscopic extraction for common bile duct stones, and it does not increase the rate of procedure-related complications.

NCT ID: NCT03924804 Completed - Clinical trials for Cholecystolithiasis and Thyroid Nodule

Effect of Different Infusion Volume on Perioperative Bladder and Blood Volume in Patients Undergoing Daytime Surgery.

Start date: June 19, 2019
Phase: N/A
Study type: Interventional

The objective of the trial was to explore the effect of different infusion volume on perioperative bladder and blood volume in patients undergoing daytime surgery assisted by bladder and vascular ultrasound and transthoracic echocardiography.

NCT ID: NCT03804775 Completed - Dyslipidemias Clinical Trials

Comparative Analysis of Serum Lipid Profiles in Patients With and Without Gallstones

Start date: August 1, 2017
Phase:
Study type: Observational

Gallbladder disease is one of the most common diseases of the gastrointestinal tract. Various studies have shown an association between gallstones and an alteration in the serum lipids. The objective of this study will be to compare serum lipid profile of gallstone patients with the controls.