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Cholecystolithiasis clinical trials

View clinical trials related to Cholecystolithiasis.

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NCT ID: NCT06340594 Completed - Biliary Stones Clinical Trials

Single-stage ERCP and Laparoscopic Cholecystectomy for Cholecystocholedocholithiasis: Which to Start With?

Start date: January 1, 2021
Phase:
Study type: Observational

Chronic calculous cholecystitis is associated with common bile duct (CBD) stones in approximately 12% of patients. These patients need both cholecystectomy and CBD clearance of stones. The standard for cholecystectomy is laparoscopic cholecystectomy (LC) and the mostly common treatment used for CBD clearance is Endoscopic Retrograde Cholangiopancreatography (ERCP). The two interventions can be combined to be done at the same time under single anesthesia session. Studies of single stage ERCP+LC showed confirmed the safety and efficacy of the combined technique. However, some surgeons start with the ERCP while others start with LC.The aim of this study is to compare the start with ERCP followed by LC to the start with LC followed by ERCP when the two techniques are combined at the same session for treatment of chronic calculous cholecystitis associated with CBD stones regarding efficacy and safety of the two approaches.

NCT ID: NCT06339437 Completed - Cholelithiases Clinical Trials

Enhanced Recovery After Cholecystectomy

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

this study will be conducted involving patients of all genders between the ages of 20 and 60 years who will undergo elective laparoscopic cholecystectomy for uncomplicated symptomatic gallstone disease. The study will be conducted in Department of West Surgical Ward, Mayo Hospital, Lahore, after receiving approval from the hospital's Ethical Committee. Patients having other co-morbid conditions, pregnant patients, and those undergoing laparoscopic cholecystectomy converted to open surgery will be excluded from the study. LFTs and other baseline investigations will be done routinely of every patient. Written informed consent will be obtained from all the patient. Patients will be divided into two groups with 30 patients in each group. Group A will consist of patient in whom ERAS protocol will be implemented and Group B in whom ERAS protocol will not be implemented.

NCT ID: NCT06258824 Completed - Pancreatic Cancer Clinical Trials

MicroRNAs as Bile-based Biomarkers in Pancreaticobiliary Cancers

MIRABILE
Start date: January 1, 2018
Phase:
Study type: Observational

pancreatic or biliary-tract cancer can be a serious diagnosis, as many patients present too late for surgery. Cancer cells have been found to release small messenger molecules called that regulate cancer genes called microRNAs (miRNAs). The goal of this observational study is to learn about the role of miRNAs from bile and blood samples in patients with pancreatic cancer and bile duct cancer. The main question[s] it aims to answer are: - Can this detect patients presenting with jaundice (yellow-skin) undergoing endoscopy? - Can this distinguish between the types of cancer? Participants will have blood and bile samples collected prior to diagnosis and their clinical pathway will be followed up for 6 months.

NCT ID: NCT06244589 Completed - Cholelithiasis Clinical Trials

Evaluation of Risk Factors Leading to Conversion From Laparoscopic Cholecystectomy to Open Surgery

Start date: February 12, 2024
Phase: N/A
Study type: Interventional

This retrospective controlled study aims to evaluate risk factors that affect open conversion in laparoscopic cholecystectomy. Patient characteristics, medical history, biochemical and radiological studies of the patient will searched from the hospital database and factors affecting open conversion will be analysed.

NCT ID: NCT06130163 Completed - Clinical trials for Cholelithiasis, Common Bile Duct

Intraoperative ERCP Versus Therapeutic Splitting in Cholecysto-, Choledocholithiasis

Start date: January 1, 2020
Phase:
Study type: Observational

At our hospital (Kepler University Hospital Linz) we perform all variants of ERCP (preoperative, intraoperative, postoperative ERCP). In cases of simultaneous cholecysto- and choledocholithiasis. Hardly any other hospital in Austria prefers intraoperative ERCP or offers it at all. We have established a standardized procedure with implemented logistics. We want to compare intraoperative and postoperative ERCP.

NCT ID: NCT06115941 Completed - Cholelithiasis Clinical Trials

Using Pre-op Incentive Spirometer Reduces Chances of Basal Atelectasis in Patients Undergoing Upper Abdominal Surgeries

Start date: March 29, 2023
Phase: N/A
Study type: Interventional

ABSTRACT Objective: To compare frequency of basal atelectasis in patients undergoing upper abdominal surgery who are provided pre-operative incentive spirometry versus those not provided pre-operative incentive spirometry

NCT ID: NCT06064331 Completed - Appendicitis Clinical Trials

Effect of Intravenous Lignocaine Infusion on Intraoperative End Tidal Desflurane Concentration Requirements

Start date: January 21, 2021
Phase: N/A
Study type: Interventional

Lignocaine is a local anaesthetic that is widely used in all medical and surgical fields. Many clinical studies have shown that intravenous (IV) lignocaine given in the perioperative period was safe, reduced airway complications, obtunds cough reflex, reduce sore throat, pain, opioid consumption, nausea, length of hospital stay. Multiple animal studies have shown that IV lignocaine was able to lower anaesthetic gas requirements. Desflurane is an anaesthetic gas that has a rapid onset and offset of action. This study aims to evaluate the effect of IV lignocaine infusion on desflurane requirements. Hypothesis of the study is that IV lignocaine infusion reduces desflurane requirements.

NCT ID: NCT05945511 Completed - Clinical trials for Kidney Transplantation

Silent Gallbladder Stone in Kidney Transplantation Recipients: Should it be Treated?

Start date: September 7, 2022
Phase:
Study type: Observational

Treatment and follow-up strategies for silent gallbladder (GB) stones in patients before KT (Kidney transplantation) remain unknown. Therefore, we aimed to assess the risk of gallstone-related biliary complications and post-cholecystectomy complications in KT recipients, to elucidate the role of prophylactic cholecystectomy in this population.

NCT ID: NCT05935969 Completed - Efficacy Clinical Trials

ETGBD in Surgically Unfit Patients With Both Choledocholithiasis and Cholecystolithiasis

ETGBD
Start date: August 1, 2022
Phase:
Study type: Observational

Cholecystectomy is recommended for patients with both gallbladder (GB) and common bile duct (CBD) stones to prevent recurrent biliary complications, unless there are specific reasons for surgery is considered inappropriate. The aim of this study was to evaluate the role of transpapillary gallbladder stent placement in surgically unfit patients with both CBD stone and gallstone.

NCT ID: NCT05827445 Completed - Cholecystolithiasis Clinical Trials

Cutaneous Sensory Block Area of the Laparoscopic Assisted Transversus Abdominis Plane Block

Start date: February 15, 2022
Phase:
Study type: Observational

The goal of this observational study is to assess the size and location of cutaneous sensory block area after dual laparoscopic assisted transverse abdominis plane block (L-TAP) with ropivacaine in patients undergoing laparoscopic cholecystectomy. L-TAP is applied as a medial subcostal infiltration between midclavicular and central sternal lines and a lateral subcostal infiltration between midclavicular and anterior axillary line bilaterally.