Childhood Glaucoma Clinical Trial
Official title:
Efficacy and Safety of Prostaglandin Analogue and Carbonic Anhydrase Inhibitor for the Treatment of Pediatric Glaucoma
Objectives:
The study will assess the ocular hypotensive effect of latanoprost and dorzolamide in a
selected sample of patients affected by primary Pediatric Glaucoma (PG), refractory to
surgical procedures. Safety will be assessed, too.In the first version of the protocol 96
eyes were forecasted to complete the enrolment. The protocol was then amended and now to
complete the study 68 eyes should be included. This number of eyes could be achieved by
recruiting from 34 to 68 patients due to not in all patients both eyes should be eligible for
the study.
Study design:
Single arm, prospective, experimental study. Due to ethical reasons and in order to adhere as
much as possible to current clinical practice, the presence of a control arm is not planned.
Due to the non-comparative nature of the study, no blinding of treatment is planned.
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