Clinical Trials Logo
  1. Home
  2. Childhood Cancer
  3. NCT04202094

Fertility in Young Adults Who Did (Not) Store Testicular Tissue Before a Treatment Leading to Fertility Problems

Childhood Cancer Clinical Trial

Official title:
Follow-up of Fertility in Young Adults Who Did or Did Not Store Testicular Tissue Before Gonadotoxic Treatment for Fertility Preservation

Clinical Trial Summary

The goal of this prospective comparative interventional cohort study is to assess the fertility status of young adult men (≥18 years) who received gonadotoxic treatment during childhood for the treatment of cancer or hematological disorders. These treatment protocols are highly gonadotoxic (i.e. they may cause later fertility problems) and therefore these patients have been proposed to store some testicular tissue during childhood as an option to preserve their fertility. The main questions this study aims to answer are (1) the impact of the received gonadotoxic treatment on the later fertility status and (2) the additional impact of a testicular biopsy procedure (performed at a young age to harvest testicular tissue for storage) on the future fertility. Participants will be asked to undergo a physical examination by a fertility specialist, to undergo a scrotal ultrasound, to give a blood sample, and to provide a semen sample. Researchers will compare the patients' fertility status between the different received gonadotoxic treatment protocols, between patients who underwent a testicular biopsy procedure at a young age and those who did not, and compare the patients' fertility status with the reproductive health of spontaneously conceived young adults.

Clinical Trial Description

See the subsequent protocol sections. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04202094
Study type Interventional
Source Universitair Ziekenhuis Brussel
Contact
Status Enrolling by invitation
Phase N/A
Start date September 8, 2020
Completion date December 2030
View Details
See also
  Status Clinical Trial Phase
Active, not recruiting NCT03336931 - PRecISion Medicine for Children With Cancer
Not yet recruiting NCT05048771 - Fertility and Temporality in Pediatric Oncology
Completed NCT05982379 - Motivation Program for Children With Cancer N/A
Completed NCT04066218 - Sexual Function Screening in Childhood Cancer Survivors
Completed NCT03934060 - Strength Training and ADLs in Childhood Leukemia and Lymphoma Patients N/A
Active, not recruiting NCT03938324 - Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions N/A
Active, not recruiting NCT04032743 - Risk Factors and Treatment Outcome of Oncology Children Hospitalized in the Intensive Care Unit Due to Sepsis
Active, not recruiting NCT04328350 - Social Experiences of Adolescents and Young Adults With Cancer
Not yet recruiting NCT05457153 - Technology-Based Well-Being Process Program (WEBEPROP) for Children and Adolescents in Palliative Care N/A
Recruiting NCT05641961 - Mobile App to Help Survivors of Childhood Cancer Navigate Long-Term Follow-Up Care N/A
Completed NCT06179914 - Resilience Models in Adolescence and Youth With Cancer in Taiwan
Completed NCT03951246 - Cognitive and Motor Training in Pediatric Posterior Fossa Tumor Survivors N/A
Not yet recruiting NCT04902313 - Cultivating Resilience in Oncology Practice N/A
Completed NCT03160768 - Feasibility of Isolating P16 Expression
Recruiting NCT06411704 - Remote Exercise Video Adaptations to Maximize Physical Activity in Childhood Cancer
Recruiting NCT06053268 - Mindfulness Interventions to Improve Health Activation, Coping, and Stress Among Childhood Cancer Survivors N/A
Withdrawn NCT02130934 - Cardiac 3D MRI in Pediatric Cancer Patients N/A
Completed NCT02216604 - Exercise in Pediatric Cancer Patient Undergoing Anti-Cancer Treatment N/A
Recruiting NCT03852758 - Green Exercise for Cancer - Creating Opportunities for Survivors N/A
Not yet recruiting NCT05754840 - CANnabinoids in Pediatric ONCology Phase 1/Phase 2