Child Survival Clinical Trial
— MVPOfficial title:
A Pair-matched Community Intervention Trial to Assess the Impact of an Integrated Health and Development Intervention on Child Survival and the Millennium Development Goals in 10 Sub- Saharan African Countries
| Verified date | April 2017 |
| Source | Columbia University |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Interventional |
The Millennium Villages Project involves the coordinated and simultaneous delivery of a
package of proven interventions in health, agriculture, infrastructure and education. The
project works in partnership with governments in 10 African countries in areas where
progress towards achieving the Millennium Development Goals has been insufficient.
The Project evaluation will test the following hypotheses:
1. That after 5 years of operation, villages exposed to the MVP intervention will have a
lower rate of under-5 mortality and parallel gains in MDG-related secondary outcomes
when compared to similar villages not receiving the intervention.
2. That the coordinated delivery a multi-sector package of health and development
interventions implemented through a broad-based local partnership is feasible in a
diversity of sub-Saharan African contexts, and;
3. The intervention package can be delivered at a scalable cost of $40 per person per year
in the health sector and $110 per person per year in total
| Status | Completed |
| Enrollment | 65000 |
| Est. completion date | June 25, 2016 |
| Est. primary completion date | June 25, 2016 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 15 Years and older |
| Eligibility |
Inclusion Criteria: - Resident in a Millennium Village and consenting to periodic assessments Exclusion Criteria: - Those not consenting to participate |
| Country | Name | City | State |
|---|---|---|---|
| Ethiopia | Koraro | Koraro | |
| Ghana | Bonsasso | Bonsasso | |
| Kenya | Sauri | Sauri | |
| Malawi | Mwandama | Mwandama | |
| Mali | Tiby | Tiby | |
| Nigeria | Ikaram | Ikaram | |
| Nigeria | Pampaida | Pampaida | |
| Rwanda | Mayange | Mayange | |
| Senegal | Potou | Potou | |
| Tanzania | Mbola | Mbola | |
| Uganda | Ruhiira | Ruhiira |
| Lead Sponsor | Collaborator |
|---|---|
| Columbia University | Bill and Melinda Gates Foundation, United Nations |
Ethiopia, Ghana, Kenya, Malawi, Mali, Nigeria, Rwanda, Senegal, Tanzania, Uganda,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Child Mortality Rate | Under 5 Mortality Rate | 5 years | |
| Secondary | Prevalence of Stunting | Proportion of under 5s who are stunted; Stunted = low height for age Z-score | 5 years | |
| Secondary | Prevalence of Diarrhea | Proportion of under 5's with diarrhea in past 2 weeks | 5 years | |
| Secondary | Prevalence of Malaria | Prevalence of malaria among under 5s at the time of survey | 5 years | |
| Secondary | Prevalence of antenatal care | Proportion of women who receive at least 4 ANC visits | 5 years | |
| Secondary | Survival rate to last grade of primary education (School Quality) | 5 years | ||
| Secondary | Prevalence of improved sanitation utilization | Proportion of the population using an improved sanitation source | 5 years | |
| Secondary | Duration or breast feeding (Child feeding practices) | 5 years | ||
| Secondary | Age of introduction of complementary feeding (Child feeding practices) | 5 years | ||
| Secondary | Prevalence of bed net utilization | Proportion of under 5s sleeping under Longlasting insecticide treated bednets in the night prior to the survey | 5 years | |
| Secondary | Prevalence of malaria treatment | Proportion of under 5s with a fever in the past 2 weeks who receive appropriate anti-malarial treatment | 5 years | |
| Secondary | Prevalence of measles immunization | Proportion under 1s immunized against measles | 5 years | |
| Secondary | Prevalence of diarrhea management | Proportion of under 5s with diarrhea in the past 2 weeks who received oral rehydration therapy | 5 years | |
| Secondary | Prevalence of pneumonia management | Proportion of under 5s treated for pneumonia in the past 2 weeks | 5 years | |
| Secondary | Prevalence of newborn care | Proportion of newborns receiving a post-natal check in the first week of life | 5 years | |
| Secondary | Proportion of pregnant women who received and HIV test | This measures the prevention of vertical transmission of HIV | 5 years | |
| Secondary | Prevalence of food insecurity | Proportion of households reporting not enough food for 1 of past 12 months | 5 years | |
| Secondary | Institutional delivery rate | Proportion of births attended by skilled health personnel | 5 years | |
| Secondary | Prevalence of underweight | Proportion of under 5s who are underweight; Underweight= weight for age Z score | 5 years | |
| Secondary | Prevalence of wasting | Proportion of under 5s who are wasted; Wasting = weight for height Z score | 5 years | |
| Secondary | Prevalence of low mid-upper arm circumference | Proportion of under 5s with a low mid-upper arm circumference | 5 years | |
| Secondary | Household Asset Index (Household poverty) | Survey of fixed and non-fixed assets, including recent purchases | 5 years | |
| Secondary | Prevalence of improved water source utilization | Proportion of the population using an improved drinking water source | 5 years |