Chikungunya Fever Clinical Trial
Official title:
Investigate the Prevalence of Serum Chikungunya Virus Infection, and Against Those Suspected Dengue Fever, Chikungunya Disease-related Tests Conducted
This test is to be collected during the dengue outbreak samples, including samples back in the past and forward to close the case, investigating the prevalence of serum Chikungunya virus infection, and against those suspected dengue fever, Chikungunya disease-related tests conducted to clarify dengue and Chikungunya disease of clinical judgment, rapid method to detect Chikungunya virus and then develop.
During the execution of this project was ended March 1, 2012 to December 31, 2015, is
expected to gather 300 suspected dengue infection, of whom 150 dengue-negative test results,
test results of 150 dengue positive. And closed the case into prospective and retrospective
analysis of the last sample into two parts.
Case closed after part of a prospective analysis of the study, subjects were required to
complete consent forms and collect 20 ml blood samples, blood samples will be checked to
identify dengue and Chikungunya disease associated serum antigen-antibody reaction , PCR
(polymerase chain reaction) test and sequence analysis and pathogen identification and
separation, in order to identify the source of infection difference. In addition,
retrospective analysis of the last part of the specimen, sucked "after the health of the host
track dengue infection, host immune regulation changes, and possible interactions with viral
hepatitis" (KMUH-IRB-960195) collected by the inspection plan body, the number of samples
included in the plan to close the case, and contact with the subjects, changes to inform the
content of the plan to re-sign the consent form.
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