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Chickenpox clinical trials

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NCT ID: NCT00985166 Completed - Measles Clinical Trials

A Study of ProQuad in Healthy 4 to 6 Year Old Children (V221-014)

Start date: August 2000
Phase: Phase 3
Study type: Interventional

The study was conducted to determine if ProQuad may be used in place of the second dose of M-M-R II routinely given to children 4 to 6 years old who were previously immunized with M-M-R II and Varivax.

NCT ID: NCT00985153 Completed - Measles Clinical Trials

Safety, Tolerability, and Immunogenicity of 3 Frozen ProQuad Consistency Lots in Healthy Children (V221-012)(COMPLETED)

Start date: March 2000
Phase: Phase 3
Study type: Interventional

This study will compare three consistency lots of ProQuad to each other as well as to M-M-R II and Varivax, administered concomitantly at different injection sites, with respect to immunogenicity, safety, and tolerability.

NCT ID: NCT00975507 Completed - Measles Clinical Trials

ProQuad™ Versus M-M-R II™ and VARIVAX™ in Healthy Children (V221-009)(COMPLETED)

Start date: March 1998
Phase: Phase 3
Study type: Interventional

This study will compare Measles, Mumps, Rubella, and Varicella Vaccine (V221) and concomitant administration of Varivax and M-M-R II vaccines in healthy children.

NCT ID: NCT00969436 Completed - Measles Clinical Trials

Comparison of GSK Measles-mumps-rubella-varicella (MMRV) Vaccine Versus PriorixTM

Start date: November 9, 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess non-inferiority of two different vaccination regimens using GSK Biological's MMRV vaccine (two doses at 9 and 15 months) or Priorix™ (9 months) and one dose of MMRV vaccine (15 months) to the current standard of care which is Priorix™ administered at 9 months of age followed by concomitant administration of Priorix™ with Varilrix™ at 15 months of age in a measles endemic environment such as India.

NCT ID: NCT00926419 Not yet recruiting - Varicella Clinical Trials

Serological Evaluation of Varicella and Hepatitis A Vaccines Using Injector Delivery

InjHepAVar
Start date: June 2009
Phase: Phase 2/Phase 3
Study type: Interventional

This study aims to assess immunogenicity and safety of nd influence of the delivery system (needle-free injector or syringe with needle) of fractional doses (dose sparing) of two vaccines (Varicella and Hepatitis A vaccines) in children aged 13 to 30 months.

NCT ID: NCT00921999 Completed - Herpes Zoster Clinical Trials

Immune Response to Varicella-Zoster Vaccination and Infection

Start date: June 15, 2009
Phase: N/A
Study type: Observational

Background: - The common varicella-zoster virus causes both chickenpox and shingles. Both diseases cause rashes, but they can also have complications such as bacterial infections of the skin, pneumonia, or eye disease. - By drawing and studying blood samples from people who have been infected with the varicella-zoster virus or who are receiving or have received the varicella vaccine, researchers hope to learn more about the immune system s response to the virus. Objectives: - To determine the immune system s response to the varicella virus, either in its existing form or given as part of a vaccine. Eligibility: - Individuals 18 years of age and older who have had or are receiving the varicella vaccine. - Individuals 5 years of age and older who currently have chickenpox or shingles. Design: - Participants will visit the NIH Clinical Center for an initial physical examination, and will provide blood samples for evaluation. - Researchers will determine the number of samples to be taken and the amount of blood to be drawn as needed based on the participants medical history and exposure to the varicella-zoster virus. Investigators in this study will not be giving subjects either the chickenpox or shingles vaccine. They will only be looking at the response to the vaccine in persons who are receiving or have received the vaccine from their health care provider.

NCT ID: NCT00892775 Completed - Measles Clinical Trials

Immunogenicity & Safety Study of GSK Biologicals' 208136 Vaccine Formulated With New Measles and Rubella Working Seeds

Start date: June 3, 2009
Phase: Phase 2
Study type: Interventional

This study is undertaken to generate clinical data on GSK Biologicals' combined measles-mumps-rubella-varicella vaccine manufactured with measles and rubella obtained from newly established working seed viruses which are one passage further than the current working seed viruses. The measles-mumps-rubella-varicella vaccine manufactured with the current working seed viruses will serve as comparator. A seed lot system is a system according to which successive batches of a vaccine are derived from the same master seed virus. For routine production, a working seed lot is prepared from the master seed virus.

NCT ID: NCT00839917 Terminated - Measles Clinical Trials

A Study of ProQuad™ in Healthy Children in Korea (V221-023)

Start date: February 2008
Phase: Phase 3
Study type: Interventional

This study will compare ProQuad™ and concomitant administration of M-M-R™ II and Varivax™ with respect to immunogenicity, safety and tolerability. The primary hypothesis to be tested is that the antibody response rates to measles, mumps, rubella, and varicella 6 weeks after vaccination with ProQuad™ will be non-inferior to the antibody response rates after vaccination with concomitant M-M-R™ II and Varivax™.

NCT ID: NCT00830648 Completed - Varicella Clinical Trials

Safety of a Second Dose of Biken's Varicella Vaccine

Start date: January 2009
Phase: Phase 4
Study type: Interventional

The objective of the present study is to assess and document the safety of a second dose of Varicella Biken vaccine administered at 4 to 6 years of age in healthy children having previously received a first dose of Varicella Biken vaccine. All subjects will receive a second dose of Varicella vaccine (Varicella Biken) at 4 to 6 years of age. The expected total duration of follow-up (first visit to last visit) for each subject will be one month.

NCT ID: NCT00792623 Completed - Varicella Clinical Trials

Immunogenicity and Safety of GSK Biologicals' Live Attenuated Varicella Vaccine (VARILRIXTM).

Start date: September 8, 2003
Phase: Phase 2
Study type: Interventional

This study aims to assess the immunogenicity and safety of varicella vaccination in a population of autologous peripheral stem cell/ bone marrow transplantation recipients who have reached at least four months post-transplantation.