Chest Wall Disorder Clinical Trial
Official title:
Comparing Analgesic Requirements in Patients Receiving Nuss Operation Using Remifentanil or Dexmedetomidine as Anesthetic Adjuvants
Nowadays, general anaesthesia is carried under "balanced anesthesia technique" in which many
anesthetic adjuvants are used simultaneously, including opioid analgesics in order to reduce
the amount of inhalation agents. The most popular adjuvants used are remifentanil, which is
an opioid analgesic, and dexmedetomidine. Both of these agents are short acting, can be
infused with targeted concentrations, excreted shortly from the body with stable
hemodynamics.
Remifentanil, when infused for more than 2 hours, causes hyperalgesia to increase the amount
of pain postoperatively as well as the amount of opioid analgesics. However, dexmedetomidine
does not cause hyperalgesia and is known to have an opioid -sparing effect. In our center.
In this study, we aim to compare the effects of remifentanil and dexmedetomidine on
postoperative pain in patients undergoing Nuss procedure, which is a very painful operation
on the chest wall.
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