Chest Pain Clinical Trial
Official title:
Two Cohort, Pilot Study, to Identify Magnetocardiogram Characteristics That Can be Used to Classify Non Ischemic Chest Pain Patients and Myocardial Infarction Patients.
The purpose of this pilot research study is to identify the characteristics of magnetocardiograms that correlate with a non ischemic chest pain status and a myocardial infarction patient status. The study uses a non SQUID magnetocardiogram device.
Magnetocardiography (MCG) is a passive, non-contact technique to measure the electromagnetic
activity of the heart.
Heart muscle is controlled by electrical impulses that initiate contraction of the
myocardium to pump blood around the body. A wave of depolarisation and repolarisation helps
to coordinate the heart's activity which is usually measured using an electrocardiogram
(ECG) which reflects the surface electrical manifestation of myocardial depolarisation and
repolarisation
For every electrical signal there is a corresponding magnetic field, as defined by Faraday's
law of induction, and it is this magnetic field that MCG measures.
There are two key advantages of looking at the magnetic field rather than the electrical
signal. (1) The signal is not attenuated as it passes through the body, so information is
not lost and (2) changes in the action potential (for example those caused by ischemia) are
'magnified' in the magnetic field so are easier to detect by sensors that are not in direct
contact with the body.
SQUID MCG has been used widely in cardiology research, and previous clinical studies have
shown that the technology has potential for the analysis of patients with coronary artery
disease.
The aim of this pilot study is to identify characteristics of MCG that differentiate
patients with non-ischaemic chest pain from those with a myocardial infarction.
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Observational Model: Case Control, Time Perspective: Prospective
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